Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SPYM18_RS07980 Genome accession   NC_003485
Coordinates   1523862..1524644 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes MGAS8232     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1518862..1529644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS07955 (spyM18_1839) gatB 1518960..1520399 (-) 1440 WP_011018162.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  SPYM18_RS07960 (spyM18_1840) gatA 1520399..1521865 (-) 1467 WP_011018163.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SPYM18_RS07965 (spyM18_1841) gatC 1521865..1522167 (-) 303 WP_011018164.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SPYM18_RS07970 - 1522399..1522647 (-) 249 WP_032465712.1 putative PEP-binding protein -
  SPYM18_RS07975 (spyM18_1844) - 1523161..1523715 (-) 555 WP_010922604.1 cysteine hydrolase family protein -
  SPYM18_RS07980 (spyM18_1846) codY 1523862..1524644 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SPYM18_RS07985 (spyM18_1849) - 1524862..1526076 (-) 1215 WP_011018165.1 pyridoxal phosphate-dependent aminotransferase -
  SPYM18_RS07990 (spyM18_1850) - 1526307..1526759 (+) 453 WP_002983265.1 universal stress protein -
  SPYM18_RS07995 (spyM18_1852) - 1526881..1528269 (-) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  SPYM18_RS08000 (spyM18_1853) - 1528341..1529306 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=22604 SPYM18_RS07980 WP_002983278.1 1523862..1524644(-) (codY) [Streptococcus pyogenes MGAS8232]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=22604 SPYM18_RS07980 WP_002983278.1 1523862..1524644(-) (codY) [Streptococcus pyogenes MGAS8232]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504