Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   C2E46_RS08860 Genome accession   NZ_CP026082
Coordinates   1758239..1759024 (-) Length   261 a.a.
NCBI ID   WP_001133183.1    Uniprot ID   P63847
Organism   Streptococcus agalactiae strain YZ1605     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1753239..1764024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS08840 (C2E46_09160) - 1754953..1755783 (-) 831 Protein_1689 pyruvate, water dikinase regulatory protein -
  C2E46_RS08845 (C2E46_09165) - 1755794..1756423 (-) 630 WP_011074751.1 helix-turn-helix transcriptional regulator -
  C2E46_RS08850 (C2E46_09170) - 1756597..1757577 (+) 981 WP_256090139.1 3-hydroxyacyl-CoA dehydrogenase -
  C2E46_RS08855 (C2E46_09175) - 1757624..1758172 (-) 549 WP_000158744.1 cysteine hydrolase family protein -
  C2E46_RS08860 (C2E46_09180) codY 1758239..1759024 (-) 786 WP_001133183.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  C2E46_RS08865 (C2E46_09185) - 1759150..1760361 (-) 1212 WP_000688108.1 pyridoxal phosphate-dependent aminotransferase -
  C2E46_RS08870 (C2E46_09190) - 1760628..1761080 (+) 453 WP_000080032.1 universal stress protein -
  C2E46_RS08875 (C2E46_09195) - 1761136..1762518 (-) 1383 WP_000974895.1 HAD-IIB family hydrolase -
  C2E46_RS08880 (C2E46_09200) - 1762587..1763549 (+) 963 WP_161501933.1 asparaginase -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28972.08 Da        Isoelectric Point: 4.4520

>NTDB_id=224525 C2E46_RS08860 WP_001133183.1 1758239..1759024(-) (codY) [Streptococcus agalactiae strain YZ1605]
MPNLLEKTRKITSILQRSVDSLDAELPYNTMAAQLADIIDCNACIINGGGNLLGYAMKYKTNTDRVEEFFETKQFPDYYV
KSASRVYDTEANLSVDNDLSIFPVETKENFQDGITTIAPIYGGGMRLGTFIIWRNDKEFSDDDLILVEIASTVVGIQLLN
LQTENLEENIRKQTAVTMAINTLSYSEMKAVAAILGELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEYN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=224525 C2E46_RS08860 WP_001133183.1 1758239..1759024(-) (codY) [Streptococcus agalactiae strain YZ1605]
ATGCCGAATTTATTAGAAAAAACTAGAAAAATTACATCCATCTTACAGCGTTCCGTAGATAGCTTAGATGCCGAATTACC
ATATAATACAATGGCGGCTCAACTAGCTGATATTATTGACTGTAACGCATGTATTATTAATGGTGGTGGTAACTTACTTG
GCTATGCCATGAAATATAAAACAAACACTGACCGTGTGGAAGAATTTTTTGAAACAAAACAATTCCCAGATTACTATGTT
AAATCTGCTAGTCGTGTTTATGATACAGAAGCTAACTTATCAGTAGATAATGATTTGTCAATTTTCCCAGTTGAGACAAA
GGAAAACTTCCAAGATGGTATTACAACAATCGCTCCAATTTATGGTGGTGGAATGCGCTTGGGAACATTTATTATCTGGC
GTAATGATAAAGAATTTAGCGACGATGATTTGATTTTAGTTGAAATTGCAAGCACCGTTGTTGGTATTCAATTACTTAAC
CTTCAAACAGAAAATCTAGAAGAAAATATTCGTAAACAAACAGCGGTGACAATGGCTATCAACACTCTATCTTATTCAGA
AATGAAAGCTGTAGCTGCTATATTAGGAGAATTAGATGGACTTGAAGGACGCCTAACGGCATCTGTTATTGCAGACCGTA
TTGGAATTACACGTTCCGTTATTGTAAATGCTCTTCGTAAATTGGAGTCTGCGGGAATCATTGAGAGCCGCTCACTCGGT
ATGAAGGGAACATACCTCAAAGTTATTAACGAAGGTATTTTTGACAAATTAAAAGAATATAATTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(201-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63847

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

67.433

100

0.674
  codY Bacillus subtilis subsp. subtilis str. 168

51.822

94.636

0.49

Multiple sequence alignment