Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   A6J85_RS10985 Genome accession   NZ_CP020450
Coordinates   2205185..2206024 (-) Length   279 a.a.
NCBI ID   WP_061598655.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2200185..2211024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS11200 (A6J85_11100) - 2200911..2201018 (-) 108 Protein_2082 DNA-entry nuclease -
  A6J85_RS10965 (A6J85_11105) - 2201311..2202357 (+) 1047 WP_105165156.1 iron ABC transporter permease -
  A6J85_RS10970 (A6J85_11110) - 2202359..2203114 (+) 756 WP_105165157.1 ABC transporter ATP-binding protein -
  A6J85_RS10975 (A6J85_10840) - 2203259..2204287 (+) 1029 WP_061601745.1 ABC transporter substrate-binding protein -
  A6J85_RS10980 (A6J85_10845) - 2204268..2204969 (+) 702 WP_061598657.1 alpha/beta hydrolase-fold protein -
  A6J85_RS10985 (A6J85_10850) endA 2205185..2206024 (-) 840 WP_061598655.1 DNA/RNA non-specific endonuclease Machinery gene
  A6J85_RS10990 (A6J85_10855) - 2206069..2206257 (-) 189 WP_060970300.1 DNA-directed RNA polymerase subunit beta -
  A6J85_RS10995 (A6J85_10860) murA 2206250..2207530 (-) 1281 WP_082307769.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  A6J85_RS11000 (A6J85_10865) - 2207570..2207803 (-) 234 WP_037622338.1 DUF1146 family protein -
  A6J85_RS11005 (A6J85_10870) tpiA 2207933..2208691 (-) 759 WP_082307770.1 triose-phosphate isomerase -
  A6J85_RS11010 (A6J85_10875) tuf 2208965..2210161 (-) 1197 WP_020992675.1 elongation factor Tu -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30842.49 Da        Isoelectric Point: 10.0100

>NTDB_id=223213 A6J85_RS10985 WP_061598655.1 2205185..2206024(-) (endA) [Streptococcus gordonii strain FDAARGOS_257]
MKKKQEEKLFQSIVGLILALVLIAGANYFSNHQNQDNIKSNPQVQRTGRRDISTPEQALSQSVLTDSVRKQLKGNIEWNQ
AGAFIINGNKTDLNADIASQPYAQNQTKSVQGQLVPIIGNALLSKQTRQYKNREETGNGTTSWVPAGWHQVRNLTGDFNH
AVDRGHLLAYSLVGGLKNFDASTSNPENIAVQTAWANQANSSSSTGQNFYESLIRKALDKKKRVRYRVTLIYANPDDLIA
AGSHLEAKSSDGSLEFNVFVPNIQTGIRINYRTGEVTVE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=223213 A6J85_RS10985 WP_061598655.1 2205185..2206024(-) (endA) [Streptococcus gordonii strain FDAARGOS_257]
ATGAAGAAGAAACAAGAAGAGAAACTTTTTCAAAGCATAGTAGGACTGATTCTGGCACTTGTTCTGATAGCTGGTGCTAA
TTATTTCTCAAACCATCAGAATCAGGATAACATAAAGTCTAATCCACAGGTTCAAAGAACAGGAAGAAGGGATATCTCAA
CTCCCGAGCAAGCACTATCTCAGAGTGTATTGACTGATTCTGTTCGCAAGCAATTAAAAGGCAACATAGAATGGAATCAG
GCAGGTGCATTTATTATTAATGGCAACAAGACAGACCTAAATGCTGATATTGCCAGTCAGCCTTATGCACAAAACCAGAC
AAAGTCAGTTCAGGGACAGTTAGTACCAATAATTGGGAATGCTCTGCTTTCTAAACAGACTAGACAATACAAAAATCGAG
AAGAAACCGGAAACGGAACGACAAGTTGGGTTCCTGCCGGCTGGCATCAAGTGAGAAATCTTACTGGAGATTTTAATCAT
GCTGTTGACCGAGGGCATTTATTAGCTTATTCTTTAGTCGGAGGCTTAAAGAACTTTGATGCTTCTACAAGTAACCCAGA
GAATATCGCTGTTCAAACAGCTTGGGCAAATCAGGCAAACAGTTCTTCGTCTACTGGACAAAATTTTTATGAAAGCTTGA
TTCGGAAGGCTTTGGATAAAAAGAAGCGAGTCCGTTATCGAGTTACCTTGATTTATGCTAATCCTGATGACTTAATAGCA
GCGGGCTCTCATTTAGAAGCAAAGTCTAGCGATGGAAGTCTTGAGTTTAATGTCTTCGTTCCAAATATTCAAACCGGGAT
TCGTATTAACTATAGAACTGGAGAAGTAACAGTAGAGTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(82-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.304

80.287

0.548
  endA Streptococcus pneumoniae D39

68.304

80.287

0.548
  endA Streptococcus pneumoniae R6

68.304

80.287

0.548
  endA Streptococcus pneumoniae TIGR4

68.304

80.287

0.548

Multiple sequence alignment