Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   A6J72_RS08875 Genome accession   NZ_CP020433
Coordinates   1759793..1760638 (+) Length   281 a.a.
NCBI ID   WP_003072166.1    Uniprot ID   A0AAD2SW28
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1754793..1765638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS08845 (A6J72_08820) - 1755162..1756040 (+) 879 WP_003069751.1 F0F1 ATP synthase subunit gamma -
  A6J72_RS08850 (A6J72_08825) atpD 1756075..1757481 (+) 1407 WP_009569014.1 F0F1 ATP synthase subunit beta -
  A6J72_RS08855 (A6J72_08830) - 1757492..1757911 (+) 420 WP_003072157.1 F0F1 ATP synthase subunit epsilon -
  A6J72_RS08860 (A6J72_08835) - 1758013..1758243 (+) 231 WP_014829739.1 DUF1146 family protein -
  A6J72_RS08865 (A6J72_08840) murA 1758281..1759561 (+) 1281 WP_009569013.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  A6J72_RS08870 (A6J72_08845) - 1759554..1759730 (+) 177 WP_003072163.1 DNA-directed RNA polymerase subunit beta -
  A6J72_RS08875 (A6J72_08850) endA 1759793..1760638 (+) 846 WP_003072166.1 DNA/RNA non-specific endonuclease Machinery gene
  A6J72_RS08880 (A6J72_08855) - 1760792..1762528 (+) 1737 WP_082312263.1 ABC transporter ATP-binding protein -
  A6J72_RS08885 (A6J72_08860) - 1762538..1764307 (+) 1770 WP_082312264.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30714.35 Da        Isoelectric Point: 10.3160

>NTDB_id=223032 A6J72_RS08875 WP_003072166.1 1759793..1760638(+) (endA) [Streptococcus intermedius strain FDAARGOS_233]
MSQRKSNQKVMQSVIGGIIALSLALGAYYFRANNNGTVHQDSSAINKSLEQHHAGPSKDLAQSVLTGNVRSQFKGKIEWN
GAGAFIVNENKNDLDAKVGSIPYADNKTKLVRGRTVPTVANALLSKATRQYRNREETGNGSTTWTPAGWHQVKHLSGEYH
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANASHSTGQNFYETKVRKALDKNKRVRYRVTLIYASEQDLV
PVGSHIEAKSSDGSLEINVFVPNVQTGIRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=223032 A6J72_RS08875 WP_003072166.1 1759793..1760638(+) (endA) [Streptococcus intermedius strain FDAARGOS_233]
ATGTCGCAGAGAAAATCCAATCAAAAAGTAATGCAGAGTGTTATTGGAGGGATTATTGCACTTAGTTTAGCTCTTGGTGC
TTATTATTTTCGAGCAAATAATAATGGTACAGTTCATCAAGATAGTTCTGCCATTAACAAAAGTCTCGAGCAACATCATG
CGGGTCCTAGTAAAGATCTGGCTCAGAGTGTATTGACAGGTAATGTGCGTTCACAATTTAAAGGGAAAATCGAGTGGAAT
GGCGCAGGAGCTTTTATTGTCAATGAGAATAAAAATGATTTAGATGCTAAAGTGGGAAGTATTCCTTATGCGGATAATAA
GACAAAATTGGTCAGAGGTCGAACTGTTCCGACGGTAGCAAATGCTCTTTTGTCCAAAGCTACTCGTCAGTATAGGAATC
GTGAAGAAACAGGTAACGGTTCAACAACTTGGACACCTGCTGGCTGGCATCAGGTGAAGCATTTATCGGGTGAATATCAT
CATGCAGTTGACCGTGGACATCTGCTAGGCTATGCCTTGATTGGTAACTTGAAAGGCTTTGATGCTTCGACTAGCAATCC
CAAAAATATTGCAGTGCAAACGGCTTGGGCGAATCAAGCAAACGCTAGCCATTCTACAGGTCAAAATTTTTATGAAACGA
AAGTACGTAAAGCTCTTGATAAAAATAAACGAGTGCGGTATCGAGTGACCTTGATTTACGCAAGTGAGCAGGATTTAGTA
CCGGTTGGTTCACATATTGAAGCCAAGTCTAGCGACGGTAGTTTGGAAATAAATGTCTTTGTGCCAAACGTACAGACAGG
AATTCGATTAAATTATCAGACAGGAGAAGTGACGGTCACCAACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(112-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.613

97.509

0.669
  endA Streptococcus pneumoniae D39

68.613

97.509

0.669
  endA Streptococcus pneumoniae R6

68.613

97.509

0.669
  endA Streptococcus pneumoniae TIGR4

68.613

97.509

0.669

Multiple sequence alignment