Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A6J40_RS15695 Genome accession   NZ_CP020412
Coordinates   3560042..3560701 (+) Length   219 a.a.
NCBI ID   WP_003635449.1    Uniprot ID   D3HKW5
Organism   Legionella longbeachae strain FDAARGOS_201     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3555042..3565701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J40_RS15665 (A6J40_15635) - 3555141..3555647 (+) 507 WP_003635433.1 LexA family transcriptional regulator -
  A6J40_RS15670 (A6J40_15640) dinB 3555840..3556907 (+) 1068 WP_085956292.1 DNA polymerase IV -
  A6J40_RS15675 (A6J40_15645) - 3557134..3557667 (-) 534 WP_125461268.1 IS630 family transposase -
  A6J40_RS15680 (A6J40_15650) - 3557633..3557959 (-) 327 WP_003635442.1 IS630 transposase-related protein -
  A6J40_RS15685 (A6J40_15655) - 3557991..3558833 (+) 843 WP_012979346.1 hypothetical protein -
  A6J40_RS15690 (A6J40_15660) phhA 3559115..3559933 (+) 819 WP_003635447.1 phenylalanine 4-monooxygenase -
  A6J40_RS15695 (A6J40_15665) letA 3560042..3560701 (+) 660 WP_003635449.1 two-component system response regulator LetA Regulator
  A6J40_RS15700 (A6J40_15670) uvrC 3560827..3562689 (+) 1863 WP_012979345.1 excinuclease ABC subunit UvrC -
  A6J40_RS15705 (A6J40_15675) - 3562916..3563629 (+) 714 WP_003635452.1 L,D-transpeptidase -
  A6J40_RS15710 (A6J40_15680) - 3563638..3564204 (+) 567 WP_172622928.1 endopeptidase IV -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24346.37 Da        Isoelectric Point: 5.1733

>NTDB_id=222453 A6J40_RS15695 WP_003635449.1 3560042..3560701(+) (letA) [Legionella longbeachae strain FDAARGOS_201]
MIKVLIVDDHALVRMGIRRLLEDMSDVEVVADAESGEQALVLVKQYSPDVVLLDMKMPGIDGWEVTRRLKKSNPHVKVIA
VTAMCSDVLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLEEAQGSPFNILSEREMQVMLMI
TSGMNVQEISDRLFLSTKTINGYRYRTFEKLGIKNDVELTYLALKHGIIENPTGLTSEE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=222453 A6J40_RS15695 WP_003635449.1 3560042..3560701(+) (letA) [Legionella longbeachae strain FDAARGOS_201]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTCGAATGGGTATTCGACGATTACTCGAAGATATGTCAGATGT
TGAAGTTGTTGCTGATGCAGAAAGTGGTGAACAAGCTTTAGTATTAGTAAAGCAATATTCCCCTGACGTAGTTCTTTTAG
ATATGAAAATGCCTGGGATAGATGGCTGGGAAGTAACCCGTCGTCTAAAAAAATCAAATCCACATGTTAAAGTCATAGCG
GTAACTGCAATGTGTTCTGATGTATTGCCCACCCGTGTTTTGCAATTAGGGGCTATGGGATATCTCACTAAAGAATCGGG
TGCTGAAGAAATGGCCGCTGCGATACGTAAGGTAGCTAAAGGGGAAAAATACCTTAGTGCTGAAATTGCTCAAAAAATGG
CAATCAACAGTTTGGAAGAAGCTCAAGGCTCACCTTTTAATATATTATCTGAACGAGAAATGCAGGTAATGTTGATGATT
ACCAGTGGCATGAATGTTCAGGAAATCAGCGATAGGCTTTTCTTGAGTACTAAAACAATCAATGGATATCGTTATCGTAC
GTTTGAGAAATTAGGTATAAAAAATGATGTTGAGCTGACCTACTTAGCTTTGAAACATGGAATCATAGAAAATCCTACTG
GTTTGACGTCAGAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3HKW5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

87.215

100

0.872
  letA Legionella pneumophila strain ERS1305867

87.215

100

0.872

Multiple sequence alignment