Detailed information NTG0022137

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: BA_RS20655
• Genome accession: NC_003997
• Coordinates: 4008951..4009745 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis str. Ames
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4003951..4014745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BA_RS20635 (BA4390)	-	4005752..4005985 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
BA_RS20640 (BA4391)	-	4006034..4006762 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
BA_RS20645 (BA4392)	-	4006813..4006959 (+)	147	WP_001247671.1	YycC family protein	-
BA_RS20650 (BA4393)	-	4007127..4008653 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
BA_RS20655 (BA4394)	spo0A	4008951..4009745 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
BA_RS20660 (BA4396)	spoIVB	4010033..4011331 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
BA_RS20665 (BA4397)	recN	4011450..4013189 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
BA_RS20670 (BA4398)	argR	4013457..4013906 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=22137 BA_RS20655 WP_003161566.1 4008951..4009745(-) (spo0A) [Bacillus anthracis str. Ames]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=22137 BA_RS20655 WP_003161566.1 4008951..4009745(-) (spo0A) [Bacillus anthracis str. Ames]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818