Detailed information NTG0219023

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: CYK58_RS03735
• Genome accession: NZ_CP025474
• Coordinates: 776275..778851 (-)
• Length: 858 a.a.
• NCBI ID: WP_126131101.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain H-137
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 771275..783851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CYK58_RS03715 (CYK58_03710)	comB10	772138..773340 (-)	1203	WP_126131098.1	DNA type IV secretion system protein ComB10	Machinery gene
CYK58_RS03720 (CYK58_03715)	-	773337..774980 (-)	1644	WP_126131099.1	TrbG/VirB9 family P-type conjugative transfer protein	-
CYK58_RS03725 (CYK58_03720)	-	774983..776146 (-)	1164	WP_126131100.1	VirB8/TrbF family protein	-
CYK58_RS08215 (CYK58_03725)	-	776139..776273 (-)	135	WP_041200005.1	hypothetical protein	-
CYK58_RS03735 (CYK58_03730)	comB4	776275..778851 (-)	2577	WP_126131101.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
CYK58_RS03740 (CYK58_03735)	-	778851..779087 (-)	237	WP_096524574.1	hypothetical protein	-
CYK58_RS03745 (CYK58_03740)	comB3	779098..779361 (-)	264	WP_001177712.1	hypothetical protein	Machinery gene
CYK58_RS03750 (CYK58_03745)	-	779372..779657 (-)	286	Protein_709	TrbC/VirB2 family protein	-
CYK58_RS03755 (CYK58_03750)	-	779654..780133 (-)	480	WP_126131102.1	hypothetical protein	-
CYK58_RS03760 (CYK58_03755)	-	780237..781020 (-)	784	Protein_711	integrase	-
CYK58_RS03765 (CYK58_03760)	ligA	781104..783077 (-)	1974	WP_126131103.1	NAD-dependent DNA ligase LigA	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98774.90 Da
• Isoelectric Point: 8.7548

>NTDB_id=219023 CYK58_RS03735 WP_126131101.1 776275..778851(-) (comB4) [Helicobacter pylori strain H-137]
MFENALKYCKEKAIDILTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDIRQNVLN
TISKGIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNEIHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTISKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIVSLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKYYPTTWKEVFVNNTYQKFDDKKHLEKVLA

Nucleotide

• Length: 2577 bp

>NTDB_id=219023 CYK58_RS03735 WP_126131101.1 776275..778851(-) (comB4) [Helicobacter pylori strain H-137]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACATTTTAACAGGTTTTGTTCCAAAAACTTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATATAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGGCATTCAATTAAGGATTGTCGCTAAAAGGCGTAAGGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAAAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGATCCATTCAAATACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCATGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGATTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGTCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAATCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGATGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCTTTGAAAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGATATTAACCAGCTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAATATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTGCCTAA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.786	97.902	0.458