NTDB

Overview

Name	codY	Type	Regulator
Locus tag	CR921_RS07970	Genome accession	NZ_CP025399
Coordinates	1521832..1522617 (-)	Length	261 a.a.
NCBI ID	WP_002951720.1	Uniprot ID	Q5M305
Organism	Streptococcus thermophilus strain GABA
Function	repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1516832..1527617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR921_RS07935	gatC	1516894..1517196 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
CR921_RS10480	-	1517336..1517497 (-)	162	WP_224103235.1	hypothetical protein	-
CR921_RS10485	-	1517529..1517801 (-)	273	WP_224103183.1	glycosyltransferase	-
CR921_RS07950	-	1518128..1519572 (-)	1445	Protein_1487	6-phospho-beta-glucosidase	-
CR921_RS07955	msrA	1519725..1520234 (-)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
CR921_RS07960	-	1520246..1521094 (-)	849	WP_024703985.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
CR921_RS07965	-	1521218..1521769 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
CR921_RS07970	codY	1521832..1522617 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
CR921_RS07975	-	1522877..1524091 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
CR921_RS07980	-	1524446..1524898 (+)	453	WP_002946987.1	universal stress protein	-
CR921_RS07985	-	1525078..1525649 (+)	572	Protein_1494	IS30 family transposase	-
CR921_RS10040	-	1525721..1525894 (-)	174	WP_011681546.1	hypothetical protein	-
CR921_RS07990	-	1525955..1526329 (-)	375	WP_011681547.1	membrane protein	-
CR921_RS07995	pflA	1526541..1527341 (-)	801	WP_101415688.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

Download Length: 261 a.a. Molecular weight: 28919.13 Da Isoelectric Point: 4.5802

                                >NTDB_id=218504 CR921_RS07970 WP_002951720.1 1521832..1522617(-) (codY) [Streptococcus thermophilus strain GABA]

MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI

RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH

LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG

MKGTYLKVLNEGIYDKLKEYE

Nucleotide

Download Length: 786 bp

                                >NTDB_id=218504 CR921_RS07970 WP_002951720.1 1521832..1522617(-) (codY) [Streptococcus thermophilus strain GABA]

ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC

ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG

GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA

CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA

AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC

GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT

CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA

AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA

TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT

ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(201-261)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q5M305

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502

Detailed information NTG0218504