Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CXP32_RS07890 Genome accession   NZ_CP025256
Coordinates   1488717..1489505 (-) Length   262 a.a.
NCBI ID   WP_000940729.1    Uniprot ID   Q97PM1
Organism   Streptococcus pneumoniae strain Xen35     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1483717..1494505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXP32_RS07865 (CXP32_07865) - 1483879..1484637 (-) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  CXP32_RS12090 - 1484845..1484991 (+) 147 WP_000403100.1 hypothetical protein -
  CXP32_RS07870 (CXP32_07870) ugpC 1485138..1486268 (-) 1131 WP_000229961.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
  CXP32_RS07875 (CXP32_07875) - 1486596..1487852 (+) 1257 WP_000436243.1 ISL3-like element IS1167A family transposase -
  CXP32_RS07885 (CXP32_07885) - 1488142..1488717 (-) 576 WP_000158721.1 isochorismatase family cysteine hydrolase -
  CXP32_RS07890 (CXP32_07890) codY 1488717..1489505 (-) 789 WP_000940729.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CXP32_RS07900 (CXP32_07900) - 1489769..1491343 (-) 1575 WP_000671113.1 DEAD/DEAH box helicase -
  CXP32_RS07905 (CXP32_07905) - 1491542..1492768 (-) 1227 WP_000841576.1 OFA family MFS transporter -
  CXP32_RS07910 (CXP32_07910) - 1492961..1494277 (+) 1317 WP_000958925.1 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29770.18 Da        Isoelectric Point: 5.7806

>NTDB_id=217922 CXP32_RS07890 WP_000940729.1 1488717..1489505(-) (codY) [Streptococcus pneumoniae strain Xen35]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPIESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=217922 CXP32_RS07890 WP_000940729.1 1488717..1489505(-) (codY) [Streptococcus pneumoniae strain Xen35]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTATTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGAAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(202-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q97PM1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

47.967

93.893

0.45