Detailed information NTG0215550

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: CV723_RS02640
• Genome accession: NZ_CP024953
• Coordinates: 523206..525782 (-)
• Length: 858 a.a.
• NCBI ID: WP_000893946.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain 7.13
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 518206..530782

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV723_RS02620 (CV723_02625)	comB10	519083..520291 (-)	1209	WP_000814183.1	DNA type IV secretion system protein ComB10	Machinery gene
CV723_RS02625 (CV723_02630)	-	520288..521943 (-)	1656	WP_000617227.1	TrbG/VirB9 family P-type conjugative transfer protein	-
CV723_RS02630 (CV723_02635)	-	521940..523076 (-)	1137	WP_000067692.1	VirB8/TrbF family protein	-
CV723_RS08400 (CV723_02640)	-	523069..523209 (-)	141	WP_000789929.1	hypothetical protein	-
CV723_RS02640 (CV723_02645)	comB4	523206..525782 (-)	2577	WP_000893946.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
CV723_RS02645 (CV723_02650)	-	525782..526018 (-)	237	WP_001168532.1	hypothetical protein	-
CV723_RS02650 (CV723_02655)	comB3	526030..526293 (-)	264	WP_001177716.1	hypothetical protein	Machinery gene
CV723_RS02655 (CV723_02660)	comB2	526305..526589 (-)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
CV723_RS02660 (CV723_02665)	-	526567..526944 (-)	378	WP_000571141.1	hypothetical protein	-
CV723_RS02665 (CV723_02670)	-	526937..527167 (-)	231	WP_000189079.1	hypothetical protein	-
CV723_RS02670 (CV723_02675)	-	527170..527958 (-)	789	WP_001140571.1	hypothetical protein	-
CV723_RS02675 (CV723_02680)	-	528008..528673 (+)	666	WP_041201762.1	hypothetical protein	-
CV723_RS02680 (CV723_02685)	-	528753..529826 (-)	1074	WP_001278345.1	site-specific integrase	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98534.67 Da
• Isoelectric Point: 8.8751

>NTDB_id=215550 CV723_RS02640 WP_000893946.1 523206..525782(-) (comB4) [Helicobacter pylori strain 7.13]
MLESALKYCKEKAIDLLAGFVPKTYSMAQECNILGLYDDTFIITKQENLVGIISLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNIYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSINEELEES
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSATSKRALLIQTIERVKNALKEFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQNTFCACVGIKAYESEEISSIPISTLLHTKIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVAETIGLKPSYF
SFFPNNANINPRMRHQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNADILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEIMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2577 bp

>NTDB_id=215550 CV723_RS02640 WP_000893946.1 523206..525782(-) (comB4) [Helicobacter pylori strain 7.13]
ATGTTAGAAAGCGCCCTTAAATATTGCAAGGAAAAAGCCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GGCACAGGAGTGCAATATTTTAGGCTTGTATGATGATACTTTCATTATTACCAAACAAGAAAATCTAGTAGGCATTATAT
CCTTACAAGGACTAAGCTATTCTAATTTAATGCAAAAAGACTTAGAGGGCTATTTTGATACTAGACAAAATGTTCTCAAC
ACCATTAGTAAAGACATTCAATTAAGAATTGTGGCTAAAAGGCGTAAGGAATTTATCAATCAAAGTCCAAATATTGACAA
TATTTATGCCAAAGCTATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAATGAAGAGTTAGAAGAAAGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CTCTTAAAGAATTTAAACCCACTTTACTAAATTCTAAAGAAGTATTAAATTTCTACGCAGAATACATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAACACCTTTTGTGCGTGTGTGGGGATTAAGGCTTATGAGAGCGAAGAAATTTCTTCGATCC
CTATATCTACTCTTTTACACACCAAAATTGAACTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCCTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTAGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTGCAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAACCCTAGAATGAGACATCAAACTTCCCAAGTCATAGCATCTTTGATTTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCTTGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCCTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAATGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTG
TCAATGCCATTGTTAAAACCAATGCAGACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGTCTAGATTTTAAAACTCGTATTAGCACCATAAATACCGATAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCCTACTATGTCTTTCATAAGATGATTGACAGAGCCTTAAGAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATAATGAATAAAAAAATCAATGAAATCATTACTCAAGCTAGAAAGGCTAATGGG
GTGATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.786	97.902	0.458