Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   BEI49_RS19400 Genome accession   NZ_CP018933
Coordinates   3597084..3597863 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus cereus strain ISSFR-9F     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3562761..3636688 3597084..3597863 within 0


Gene organization within MGE regions


Location: 3562761..3636688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEI49_RS19235 - 3563104..3564774 (-) 1671 WP_000823085.1 ribonuclease J -
  BEI49_RS19245 dapA 3565540..3566418 (-) 879 WP_000564761.1 4-hydroxy-tetrahydrodipicolinate synthase -
  BEI49_RS19250 dapG 3566430..3567662 (-) 1233 WP_000692470.1 aspartate kinase -
  BEI49_RS19255 asd 3567686..3568732 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  BEI49_RS19260 dpaB 3568883..3569482 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  BEI49_RS19265 dpaA 3569479..3570381 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  BEI49_RS19275 - 3570656..3570907 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  BEI49_RS19280 - 3571034..3572275 (-) 1242 WP_000592993.1 M16 family metallopeptidase -
  BEI49_RS19285 - 3572362..3573261 (-) 900 WP_000647532.1 polysaccharide deacetylase family protein -
  BEI49_RS19290 pnp 3573413..3575551 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  BEI49_RS19295 rpsO 3575712..3575981 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  BEI49_RS19300 ribF 3576082..3577053 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  BEI49_RS19305 truB 3577097..3578020 (-) 924 WP_000399337.1 tRNA pseudouridine(55) synthase TruB -
  BEI49_RS19310 rbfA 3578107..3578463 (-) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  BEI49_RS19315 - 3578479..3578760 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  BEI49_RS19320 infB 3578757..3580817 (-) 2061 WP_000036341.1 translation initiation factor IF-2 -
  BEI49_RS19325 - 3580822..3581133 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  BEI49_RS19330 rnpM 3581134..3581406 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  BEI49_RS19335 nusA 3581418..3582524 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  BEI49_RS19340 rimP 3582542..3583012 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  BEI49_RS19345 - 3583345..3587646 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  BEI49_RS19355 - 3587771..3589471 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  BEI49_RS19360 rseP 3589581..3590837 (-) 1257 WP_001090229.1 RIP metalloprotease RseP -
  BEI49_RS19365 dxr 3590854..3591996 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  BEI49_RS19370 cdsA 3592020..3592811 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  BEI49_RS19375 uppS 3592829..3593605 (-) 777 WP_000971301.1 isoprenyl transferase -
  BEI49_RS19380 frr 3593691..3594248 (-) 558 WP_000531503.1 ribosome recycling factor -
  BEI49_RS19385 pyrH 3594251..3594973 (-) 723 WP_000042663.1 UMP kinase -
  BEI49_RS19390 tsf 3595040..3595927 (-) 888 WP_001018581.1 translation elongation factor Ts -
  BEI49_RS19395 rpsB 3596031..3596732 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  BEI49_RS19400 codY 3597084..3597863 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  BEI49_RS19405 hslU 3597941..3599332 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  BEI49_RS19410 hslV 3599355..3599897 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  BEI49_RS19415 xerC 3599940..3600839 (-) 900 WP_001101227.1 tyrosine recombinase XerC -
  BEI49_RS19420 trmFO 3600905..3602209 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  BEI49_RS19425 topA 3602260..3604338 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  BEI49_RS19430 dprA 3604483..3605352 (-) 870 WP_000818032.1 DNA-processing protein DprA -
  BEI49_RS19435 sucD 3605440..3606342 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  BEI49_RS19440 sucC 3606362..3607522 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  BEI49_RS19445 rnhB 3607716..3608489 (-) 774 WP_001174714.1 ribonuclease HII -
  BEI49_RS19450 ylqF 3608541..3609431 (-) 891 WP_000236696.1 ribosome biogenesis GTPase YlqF -
  BEI49_RS19455 lepB 3609452..3610003 (-) 552 WP_000711857.1 signal peptidase I -
  BEI49_RS19460 rplS 3610105..3610449 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  BEI49_RS19465 trmD 3610596..3611330 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BEI49_RS19470 rimM 3611330..3611845 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  BEI49_RS19475 - 3611966..3612193 (-) 228 WP_000737398.1 KH domain-containing protein -
  BEI49_RS19480 rpsP 3612208..3612480 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  BEI49_RS19485 ffh 3612581..3613930 (-) 1350 WP_000863461.1 signal recognition particle protein -
  BEI49_RS19490 - 3613943..3614275 (-) 333 WP_000891062.1 putative DNA-binding protein -
  BEI49_RS19495 ftsY 3614410..3615399 (-) 990 WP_000007649.1 signal recognition particle-docking protein FtsY -
  BEI49_RS19500 smc 3615415..3618984 (-) 3570 WP_075396456.1 chromosome segregation protein SMC -
  BEI49_RS19505 rncS 3619131..3619868 (-) 738 WP_001146873.1 ribonuclease III -
  BEI49_RS19510 acpP 3619927..3620160 (-) 234 WP_000786062.1 acyl carrier protein -
  BEI49_RS19515 fabG 3620230..3620970 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  BEI49_RS19520 fabD 3620970..3621914 (-) 945 WP_000516948.1 ACP S-malonyltransferase -
  BEI49_RS19525 plsX 3621929..3622921 (-) 993 WP_000684110.1 phosphate acyltransferase PlsX -
  BEI49_RS19530 fapR 3622918..3623511 (-) 594 WP_000747352.1 transcription factor FapR -
  BEI49_RS19535 recG 3623600..3625648 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  BEI49_RS19540 - 3625938..3627614 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  BEI49_RS19545 - 3627637..3627999 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  BEI49_RS19550 rpmB 3628378..3628566 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  BEI49_RS19555 spoVM 3628640..3628720 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  BEI49_RS19560 - 3628787..3629467 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  BEI49_RS19565 rpe 3629567..3630211 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  BEI49_RS19570 rsgA 3630214..3631095 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  BEI49_RS19575 prkC 3631364..3633337 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  BEI49_RS19580 - 3633346..3634098 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BEI49_RS19585 rlmN 3634103..3635191 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  BEI49_RS19590 rsmB 3635196..3636530 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=212144 BEI49_RS19400 WP_000421288.1 3597084..3597863(-) (codY) [Bacillus cereus strain ISSFR-9F]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=212144 BEI49_RS19400 WP_000421288.1 3597084..3597863(-) (codY) [Bacillus cereus strain ISSFR-9F]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAACTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment