Detailed information NTG0210104

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: BXP02_RS02645
• Genome accession: NZ_CP024074
• Coordinates: 522044..524620 (-)
• Length: 858 a.a.
• NCBI ID: WP_000893946.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain 7.13_R2a
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 517044..529620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BXP02_RS02625 (BXP02_02620)	comB10	517921..519129 (-)	1209	WP_000814183.1	DNA type IV secretion system protein ComB10	Machinery gene
BXP02_RS02630 (BXP02_02625)	-	519126..520781 (-)	1656	WP_000617227.1	TrbG/VirB9 family P-type conjugative transfer protein	-
BXP02_RS02635 (BXP02_02630)	-	520778..521914 (-)	1137	WP_000067692.1	VirB8/TrbF family protein	-
BXP02_RS08410 (BXP02_02635)	-	521907..522047 (-)	141	WP_000789929.1	hypothetical protein	-
BXP02_RS02645 (BXP02_02640)	comB4	522044..524620 (-)	2577	WP_000893946.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
BXP02_RS02650 (BXP02_02645)	-	524620..524856 (-)	237	WP_001168532.1	hypothetical protein	-
BXP02_RS02655 (BXP02_02650)	comB3	524868..525131 (-)	264	WP_001177716.1	hypothetical protein	Machinery gene
BXP02_RS02660 (BXP02_02655)	comB2	525143..525427 (-)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
BXP02_RS02665 (BXP02_02660)	-	525405..525782 (-)	378	WP_000571141.1	hypothetical protein	-
BXP02_RS02670 (BXP02_02665)	-	525775..526005 (-)	231	WP_000189079.1	hypothetical protein	-
BXP02_RS02675 (BXP02_02670)	-	526008..526796 (-)	789	WP_001140571.1	hypothetical protein	-
BXP02_RS02680 (BXP02_02675)	-	526846..527511 (+)	666	WP_041201762.1	hypothetical protein	-
BXP02_RS02685 (BXP02_02680)	-	527591..528664 (-)	1074	WP_001278345.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98534.67 Da
• Isoelectric Point: 8.8751

>NTDB_id=210104 BXP02_RS02645 WP_000893946.1 522044..524620(-) (comB4) [Helicobacter pylori strain 7.13_R2a]
MLESALKYCKEKAIDLLAGFVPKTYSMAQECNILGLYDDTFIITKQENLVGIISLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNIYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSINEELEES
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSATSKRALLIQTIERVKNALKEFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQNTFCACVGIKAYESEEISSIPISTLLHTKIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVAETIGLKPSYF
SFFPNNANINPRMRHQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNADILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEIMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2577 bp

>NTDB_id=210104 BXP02_RS02645 WP_000893946.1 522044..524620(-) (comB4) [Helicobacter pylori strain 7.13_R2a]
ATGTTAGAAAGCGCCCTTAAATATTGCAAGGAAAAAGCCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GGCACAGGAGTGCAATATTTTAGGCTTGTATGATGATACTTTCATTATTACCAAACAAGAAAATCTAGTAGGCATTATAT
CCTTACAAGGACTAAGCTATTCTAATTTAATGCAAAAAGACTTAGAGGGCTATTTTGATACTAGACAAAATGTTCTCAAC
ACCATTAGTAAAGACATTCAATTAAGAATTGTGGCTAAAAGGCGTAAGGAATTTATCAATCAAAGTCCAAATATTGACAA
TATTTATGCCAAAGCTATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAATGAAGAGTTAGAAGAAAGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CTCTTAAAGAATTTAAACCCACTTTACTAAATTCTAAAGAAGTATTAAATTTCTACGCAGAATACATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAACACCTTTTGTGCGTGTGTGGGGATTAAGGCTTATGAGAGCGAAGAAATTTCTTCGATCC
CTATATCTACTCTTTTACACACCAAAATTGAACTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCCTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTAGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTGCAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAACCCTAGAATGAGACATCAAACTTCCCAAGTCATAGCATCTTTGATTTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCTTGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCCTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAATGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTG
TCAATGCCATTGTTAAAACCAATGCAGACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGTCTAGATTTTAAAACTCGTATTAGCACCATAAATACCGATAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCCTACTATGTCTTTCATAAGATGATTGACAGAGCCTTAAGAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATAATGAATAAAAAAATCAATGAAATCATTACTCAAGCTAGAAAGGCTAATGGG
GTGATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.786	97.902	0.458