Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CRD75_RS07385 Genome accession   NZ_CP023769
Coordinates   1449271..1450053 (-) Length   260 a.a.
NCBI ID   WP_021340905.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HarveyGAS     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1444271..1455053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRD75_RS07355 (CRD75_07355) gatB 1444369..1445808 (-) 1440 WP_002983292.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  CRD75_RS07360 (CRD75_07360) gatA 1445808..1447274 (-) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  CRD75_RS07365 (CRD75_07365) gatC 1447274..1447576 (-) 303 WP_011285093.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  CRD75_RS07370 (CRD75_07370) - 1447808..1448032 (-) 225 WP_014635660.1 putative PEP-binding protein -
  CRD75_RS07380 (CRD75_07380) - 1448570..1449124 (-) 555 WP_002988559.1 isochorismatase family cysteine hydrolase -
  CRD75_RS07385 (CRD75_07385) codY 1449271..1450053 (-) 783 WP_021340905.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CRD75_RS07390 (CRD75_07390) - 1450271..1451485 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  CRD75_RS07395 (CRD75_07395) - 1451716..1452168 (+) 453 WP_002992571.1 universal stress protein -
  CRD75_RS07400 (CRD75_07400) - 1452291..1453679 (-) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  CRD75_RS07405 (CRD75_07405) - 1453751..1454716 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28647.79 Da        Isoelectric Point: 4.5611

>NTDB_id=208600 CRD75_RS07385 WP_021340905.1 1449271..1450053(-) (codY) [Streptococcus pyogenes strain HarveyGAS]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASIIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=208600 CRD75_RS07385 WP_021340905.1 1449271..1450053(-) (codY) [Streptococcus pyogenes strain HarveyGAS]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTATTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.759

98.846

0.65
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504