Detailed information NTG0020700

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SMA_2122
• Genome accession: HE613569
• Coordinates: 2061528..2064098 (-)
• Length: 856 a.a.
• NCBI ID: CCF03413.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2056528..2069098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_2116	-	2056631..2057005 (-)	375	CCF03407.1	Facilitator superfamily protein	-
SMA_2117	-	2057387..2057689 (-)	303	CCF03408.1	Hypothetical protein	-
SMA_2118	-	2057708..2057851 (-)	144	CCF03409.1	Hypothetical protein	-
SMA_2119	-	2058112..2058768 (+)	657	CCF03410.1	Hypothetical protein	-
SMA_2120	ruvA	2058873..2059466 (-)	594	CCF03411.1	Holliday junction DNA helicase RuvA	Machinery gene
SMA_2121	hexB	2059468..2061411 (-)	1944	CCF03412.1	DNA mismatch repair protein MutL	Machinery gene
SMA_2122	hexA	2061528..2064098 (-)	2571	CCF03413.1	DNA mismatch repair protein MutS	Machinery gene
SMA_2123	-	2064085..2064441 (-)	357	CCF03414.1	Hypothetical protein	-
SMA_2124	argR2	2064438..2064875 (-)	438	CCF03415.1	Arginine repressor ArgR, putative	-
SMA_2125	argS	2065065..2066756 (+)	1692	CCF03416.1	Arginyl-tRNA synthetase	-
SMA_2126	-	2066868..2067161 (+)	294	CCF03417.1	Hypothetical protein	-
SMA_2127	-	2067203..2068695 (-)	1493	Protein_2126	putative BglB fragment	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96039.26 Da
• Isoelectric Point: 4.7977

>NTDB_id=20700 SMA_2122 CCF03413.1 2061528..2064098(-) (hexA) [Streptococcus macedonicus ACA-DC 198]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSFSDFSS
LRSEILNLKAREIVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQVQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPTIKAILESFESPHLDKLVNSIDTLPELESLIRSAIDP
DAPAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGISNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAHEQSASLEYDIFMRVRGQVERYITRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DNHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRSSSQSLILFDELGRGTATYDGMALAQSIIEYIHNHIGAKTMFATHYHEL
TDLSTSLTHLVNVHVATLEKNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPVVEAE
PITVKSEVAEPVAEQLSLFADDSSNQEVIEVLKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=20700 SMA_2122 CCF03413.1 2061528..2064098(-) (hexA) [Streptococcus macedonicus ACA-DC 198]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAGGCTGCACAGATTTTAGAGATTAGCTTAACTAGTC
GTAATAAAAATGCTGACAATCCAATTCCAATGGCAGGTGTCCCTTATCATTCTGCACAACAATACATTGATGTATTAGTA
GAATTGGGTTACAAGGTGGCAATTGCAGAGCAAATGGAAGACCCTAAACAAGCCGTTGGTGTGGTTAAACGTGAAGTTGT
TCAAGTGATTACACCAGGGACTGCGGTTGATTCTTCTAAACCAGATAATGCTAATAATTTCTTGGTGGCTATTGACTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGATGTGTCAACAGGTGAATTTTTCTCAACAAGTTTTTCTGATTTTTCAAGT
CTTAGGAGTGAAATTCTGAACCTTAAAGCGCGTGAAATTGTTGTTGGCTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTACATTTAATCGACCCAGATTTAACGG
CCTTAGAAATTTCAGCAGCTGAGAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGTCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTACACGACAAAATCTAGTCTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTATTGCGCAATT
GGATTGACCGCCCTTTGGTGAACCAAGTACAGATTGAGGAACGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTAACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTTTAGCGAGTCGTGTGTCGTTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACCTTGGCACAAGTGCCAACAATTAAGGCAATTTTAGAATCGTTTGAAA
GCCCTCACCTTGATAAGCTTGTCAATAGCATTGACACTTTGCCAGAGCTAGAATCACTGATTCGCTCAGCTATTGACCCA
GATGCCCCTGCTGTTATCACAGAAGGCAGCATTATCCGTACAGGCTTTGATGAGACTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGCTGGATTGCAGAAATTGAGGCTAAGGAACGTGCTGCAAGTGGGATTAGCAATCTAAAAATTGATT
ATAATAAAAAAGACGGATACTATTTCCATGTGACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCTAAAATTGAAGGTGAGATGTTGGAGGCACATGAGCAATC
AGCAAGCTTAGAATATGATATTTTTATGCGCGTTCGTGGACAAGTTGAGCGTTACATTACACGTTTGCAAGACTTGGCTA
AGGCGATTTCAACCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAGAATAATCATTATGTTCGTCCAACATTCAAC
GATAACCATGAAATTAAGATTGAAAAAGGTCGTCATGCGGTTGTTGAAAAAGTTATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACAGTTATTATGGCTCAAATGGGGTCTTATGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCTGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAATCA
AGCTATCAAACGTTCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATAACCATATCGGTGCTAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGATTTGTCAACAAGCTTGACGCATCTTGTCAATGTGCACGTTGCTACCCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGAATTCATGTAGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGTATCTTGACGAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGTGGTAGAAGCTGAG
CCAATTACTGTAAAATCTGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAACCAAGA
AGTGATTGAAGTACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.963	100	0.72
mutS	Pseudomonas stutzeri strain ATCC 17587	37.601	100	0.381