Detailed information NTG0205185

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: A2U20_RS07330
• Genome accession: NZ_CP018032
• Coordinates: 1530767..1531963 (+)
• Length: 398 a.a.
• NCBI ID: WP_021117770.1
• Uniprot ID: -
• Organism: Glaesserella parasuis D74
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1525767..1536963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2U20_RS07310 (A2U20_07200)	gmk	1526450..1527076 (+)	627	WP_021117774.1	guanylate kinase	-
A2U20_RS07315 (A2U20_07205)	radA	1527129..1528505 (-)	1377	WP_021117773.1	DNA repair protein RadA	-
A2U20_RS07320 (A2U20_07210)	pilA	1528693..1529148 (+)	456	WP_021117772.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
A2U20_RS07325 (A2U20_07215)	pilB	1529389..1530774 (+)	1386	WP_021117771.1	GspE/PulE family protein	Machinery gene
A2U20_RS07330 (A2U20_07220)	pilC	1530767..1531963 (+)	1197	WP_021117770.1	type II secretion system F family protein	Machinery gene
A2U20_RS07335 (A2U20_07225)	-	1531960..1532628 (+)	669	WP_021117769.1	prepilin peptidase	-
A2U20_RS07340 (A2U20_07230)	dapE	1532712..1533845 (+)	1134	WP_021117768.1	succinyl-diaminopimelate desuccinylase	-
A2U20_RS07345 (A2U20_07235)	clpX	1533919..1535169 (-)	1251	WP_021117767.1	ATP-dependent protease ATP-binding subunit ClpX	-
A2U20_RS07350 (A2U20_07240)	clpP	1535176..1535757 (-)	582	WP_010787003.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
A2U20_RS07355 (A2U20_07245)	-	1535857..1536246 (+)	390	WP_021117766.1	SufE family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45751.55 Da
• Isoelectric Point: 10.1227

>NTDB_id=205185 A2U20_RS07330 WP_021117770.1 1530767..1531963(+) (pilC) [Glaesserella parasuis D74]
MNNIYEFQWKGRNRFGQKQTGRQLAESREVLEKRLQQKGYSQLRISRHFALPTAPKKEEINQFMQQLALLIQAKIPLKQS
LVMLLETCQNRTFYRWQQETIRLIEAGFALSVAFEKQGKYINPQEIQLIKMAETSGNLGLILTNIAQRREKSEKLTKKIK
KILFYPVFILAISITLSILLLLFIVPQFAELYGSKGKSLPLITEILFSLSNFLQHSILTLIILCVLCFLLIHILNKKTDL
IKRLKFIILSHIPILKGIIQYSRIIFFCQNSSLMLASHIRLDTVLHSFLANKSDDILLQRSLATTLTYLKQGYRLADSLD
PKLFPTDMLQMIAIGEQSGKLSPMLQQISDGYQQRLDYQIDILSQLLEPMLMVLMGIIVGTILVGLYLPIFDMGAMIE

Nucleotide

• Length: 1197 bp

>NTDB_id=205185 A2U20_RS07330 WP_021117770.1 1530767..1531963(+) (pilC) [Glaesserella parasuis D74]
ATGAATAACATTTATGAATTTCAATGGAAAGGACGCAACCGCTTTGGACAAAAGCAAACAGGGCGACAGCTTGCCGAAAG
CAGAGAAGTGCTAGAAAAACGCTTGCAACAAAAAGGCTATAGCCAGTTACGCATTAGCCGACATTTTGCCTTGCCGACGG
CACCGAAAAAGGAAGAAATTAATCAATTTATGCAACAGTTGGCATTATTAATTCAAGCCAAAATCCCCCTAAAACAGAGT
TTGGTAATGTTGCTGGAAACTTGCCAAAATCGCACCTTTTACCGTTGGCAACAAGAGACAATCCGCTTGATTGAAGCTGG
CTTTGCCCTATCCGTTGCCTTTGAAAAACAGGGGAAATATATCAATCCACAAGAGATCCAATTAATTAAAATGGCAGAAA
CAAGCGGTAATTTAGGGCTGATTTTAACCAATATTGCACAACGCCGTGAAAAATCGGAAAAACTAACCAAGAAAATTAAA
AAAATTCTCTTTTATCCCGTCTTTATTTTAGCTATTTCAATCACACTCTCTATTTTATTATTACTTTTTATTGTGCCACA
ATTTGCAGAACTTTATGGATCAAAAGGAAAATCATTACCCCTAATTACCGAAATACTCTTTAGCCTATCCAATTTTCTAC
AACACTCTATTTTAACGCTAATTATTTTATGTGTGTTATGTTTTCTATTAATTCATATTTTAAATAAAAAAACAGATCTT
ATTAAACGCCTAAAGTTTATTATATTAAGCCATATTCCTATTTTAAAAGGCATTATCCAGTATTCACGCATTATCTTTTT
TTGTCAAAATAGCAGTTTAATGCTGGCTTCACATATTCGTTTAGATACTGTACTTCATTCCTTTTTAGCCAATAAAAGTG
ATGATATTTTATTACAACGTTCTCTAGCAACTACACTAACTTATTTAAAACAAGGTTATCGTTTAGCCGACAGTTTAGAT
CCAAAACTCTTTCCTACGGATATGTTACAGATGATTGCCATTGGCGAGCAGAGCGGAAAATTATCGCCAATGTTGCAACA
AATCAGCGACGGTTATCAACAGCGGTTAGATTATCAAATTGATATACTTTCCCAATTATTAGAGCCGATGTTAATGGTGT
TAATGGGAATTATTGTAGGAACTATTTTAGTCGGGTTATATTTGCCGATTTTTGATATGGGAGCAATGATAGAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	98.744	100	0.987
pilC	Haemophilus influenzae 86-028NP	38.653	100	0.389
pilC	Haemophilus influenzae Rd KW20	38.653	100	0.389