Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SMA_0733 Genome accession   HE613569
Coordinates   728731..729597 (+) Length   288 a.a.
NCBI ID   CCF02024.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 723731..734597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_0727 atpG 724007..724885 (+) 879 CCF02018.1 ATP synthase gamma chain -
  SMA_0728 atpD 724952..726358 (+) 1407 CCF02019.1 ATP synthase beta chain -
  SMA_0729 atpC 726371..726787 (+) 417 CCF02020.1 ATP synthase epsilon chain -
  SMA_0730 - 726852..727088 (+) 237 CCF02021.1 Hypothetical protein -
  SMA_0731 murA2 727139..728425 (+) 1287 CCF02022.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SMA_0732 - 728428..728616 (+) 189 CCF02023.1 Competence-associated EpuA protein -
  SMA_0733 endA 728731..729597 (+) 867 CCF02024.1 DNA-entry nuclease (Competence-specific nuclease) Machinery gene
  SMA_0734 pheS 730460..731566 (+) 1107 CCF02025.1 Phenylalanyl-tRNA synthetase alpha chain -
  SMA_0735 paiA 731602..732126 (+) 525 CCF02026.1 Acetyltransferase, GNAT family -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 30919.11 Da        Isoelectric Point: 6.1112

>NTDB_id=20350 SMA_0733 CCF02024.1 728731..729597(+) (endA) [Streptococcus macedonicus ACA-DC 198]
MAKKSKLFKQTKSLMSLVILLVGIGTGWVTISDSTDPLNQVVSLITGDSSSEITSNQSSSDLATPTQSLAETVLTDSVKE
QLGANIEWNGAGAYIINDNQTSLNAKVSSQPYANNKTKTVQGQTVPTVANALLSKSTRQYKSREETGNGSTSWTPAGWHQ
VQDLSGTYSHAVDRGHLLGYALVGGLKGFDASTSNPDNVATQTAWANEANSESSTGQNYYESLVRKALDQKKRVRYRVTL
IYDGDNLLASGTHLEAKSSDGSLEFNVFVPNVQSGLTFDYYSGQVSVN

Nucleotide


Download         Length: 867 bp        

>NTDB_id=20350 SMA_0733 CCF02024.1 728731..729597(+) (endA) [Streptococcus macedonicus ACA-DC 198]
ATGGCAAAGAAATCAAAATTGTTTAAACAGACAAAATCCCTGATGTCTTTGGTGATTTTGTTAGTTGGTATTGGTACTGG
TTGGGTGACGATATCAGATTCGACTGACCCGCTAAATCAAGTCGTTTCGTTAATTACTGGTGACTCCTCTTCTGAAATAA
CGTCAAATCAATCAAGTTCAGATTTGGCAACGCCAACACAATCTTTAGCAGAGACGGTATTAACAGATAGTGTCAAAGAG
CAGTTAGGGGCAAATATAGAATGGAATGGTGCGGGAGCCTATATTATCAATGATAATCAAACATCCCTAAATGCAAAAGT
TTCAAGTCAACCTTACGCCAACAACAAAACGAAAACGGTGCAAGGTCAGACTGTTCCAACGGTTGCTAATGCTTTGCTAA
GTAAGTCAACTCGTCAATACAAAAGTCGTGAGGAAACAGGAAATGGGTCGACCTCTTGGACGCCTGCGGGTTGGCATCAA
GTTCAAGACCTTTCAGGGACTTATAGCCATGCGGTAGACCGTGGGCATTTGCTTGGCTATGCTTTGGTTGGTGGTCTAAA
AGGCTTTGATGCGTCAACAAGCAACCCTGACAATGTGGCAACACAGACGGCTTGGGCGAACGAGGCAAATTCGGAAAGTT
CAACTGGTCAAAATTACTATGAATCCCTTGTCCGCAAAGCTCTTGACCAGAAAAAACGAGTTCGTTATCGTGTCACCTTG
ATTTATGACGGTGATAATCTCTTAGCAAGCGGAACGCATTTGGAAGCCAAATCATCTGACGGTAGTCTAGAATTTAACGT
CTTTGTTCCAAATGTGCAAAGCGGACTGACATTTGATTATTATTCAGGTCAAGTTAGTGTGAATTGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(95-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

71.875

77.778

0.559
  endA Streptococcus pneumoniae D39

71.875

77.778

0.559
  endA Streptococcus pneumoniae R6

71.875

77.778

0.559
  endA Streptococcus pneumoniae TIGR4

71.875

77.778

0.559

Multiple sequence alignment