Detailed information NTG0201701

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB526_RS13945
• Genome accession: NZ_CP017682
• Coordinates: 2684535..2685422 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CFSAN007850
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2679535..2690422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB526_RS13910 (AB526_13610)	-	2679556..2679648 (+)	93	WP_010956583.1	hypothetical protein	-
AB526_RS13915 (AB526_13615)	-	2679756..2680253 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB526_RS13920 (AB526_13620)	-	2680263..2680523 (-)	261	WP_001791974.1	hypothetical protein	-
AB526_RS13930 (AB526_13625)	-	2680905..2681018 (-)	114	Protein_2609	hypothetical protein	-
AB526_RS13935 (AB526_13635)	-	2681677..2683677 (-)	2001	WP_099130585.1	ABC transporter permease	-
AB526_RS13940 (AB526_13640)	-	2683674..2684429 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB526_RS13945 (AB526_13645)	braS	2684535..2685422 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB526_RS13950 (AB526_13650)	braR	2685433..2686098 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB526_RS13955 (AB526_13655)	-	2686124..2686324 (-)	201	WP_000604730.1	hypothetical protein	-
AB526_RS13960 (AB526_13665)	-	2686522..2687946 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AB526_RS14745	-	2688016..2688126 (+)	111	Protein_2616	hypothetical protein	-
AB526_RS13970 (AB526_13675)	-	2688229..2688684 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB526_RS13975 (AB526_13680)	-	2688929..2689690 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=201701 AB526_RS13945 WP_000143425.1 2684535..2685422(-) (braS) [Staphylococcus aureus strain CFSAN007850]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=201701 AB526_RS13945 WP_000143425.1 2684535..2685422(-) (braS) [Staphylococcus aureus strain CFSAN007850]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1