Detailed information NTG0201611

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB478_RS09915
• Genome accession: NZ_CP017679
• Coordinates: 1949748..1950791 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN007883
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1944748..1955791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB478_RS09885 (AB478_09650)	-	1945169..1946425 (-)	1257	WP_078065149.1	aminopeptidase	-
AB478_RS09890 (AB478_09655)	-	1946428..1946628 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB478_RS09895 (AB478_09660)	-	1946775..1947239 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB478_RS09900 (AB478_09665)	-	1947246..1947521 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB478_RS09905 (AB478_09670)	-	1947799..1949016 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
AB478_RS09910 (AB478_09675)	vraR	1949129..1949758 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
AB478_RS09915 (AB478_09680)	vraS	1949748..1950791 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB478_RS09920 (AB478_09685)	liaF	1950788..1951489 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB478_RS09925 (AB478_09690)	-	1951504..1951890 (-)	387	WP_001110179.1	hypothetical protein	-
AB478_RS09930 (AB478_09695)	map	1952107..1952865 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB478_RS09940 (AB478_09700)	-	1953394..1954380 (+)	987	WP_000999708.1	FUSC family protein	-
AB478_RS09945 (AB478_09705)	-	1954813..1955226 (-)	414	WP_025174552.1	hypothetical protein	-
AB478_RS09950 (AB478_09710)	-	1955255..1955365 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=201611 AB478_RS09915 WP_001017131.1 1949748..1950791(-) (vraS) [Staphylococcus aureus strain CFSAN007883]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=201611 AB478_RS09915 WP_001017131.1 1949748..1950791(-) (vraS) [Staphylococcus aureus strain CFSAN007883]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1