Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CG712_RS04185 Genome accession   NZ_CP022547
Coordinates   805107..805892 (-) Length   261 a.a.
NCBI ID   WP_002951720.1    Uniprot ID   Q5M305
Organism   Streptococcus thermophilus strain B59671     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 800107..810892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS04150 (CG712_04185) gatC 800173..800475 (-) 303 WP_002884769.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  CG712_RS10225 - 800808..801080 (-) 273 WP_232510048.1 glycosyltransferase -
  CG712_RS04165 (CG712_04200) - 801407..802848 (-) 1442 Protein_814 6-phospho-beta-glucosidase -
  CG712_RS04170 (CG712_04205) msrA 803001..803510 (-) 510 WP_002951714.1 peptide-methionine (S)-S-oxide reductase MsrA -
  CG712_RS04175 (CG712_04210) - 803522..804370 (-) 849 WP_096811627.1 MetQ/NlpA family ABC transporter substrate-binding protein -
  CG712_RS04180 (CG712_04215) - 804493..805044 (-) 552 WP_002946999.1 cysteine hydrolase family protein -
  CG712_RS04185 (CG712_04220) codY 805107..805892 (-) 786 WP_002951720.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CG712_RS04190 (CG712_04225) - 806152..807366 (-) 1215 WP_011226456.1 pyridoxal phosphate-dependent aminotransferase -
  CG712_RS04195 (CG712_04230) - 807721..808173 (+) 453 WP_002946987.1 universal stress protein -
  CG712_RS10230 (CG712_04235) - 808350..808924 (+) 575 Protein_821 IS30 family transposase -
  CG712_RS10235 - 808996..809604 (-) 609 WP_002946982.1 hypothetical protein -
  CG712_RS04210 (CG712_04245) pflA 809816..810616 (-) 801 WP_002946980.1 pyruvate formate-lyase-activating protein -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28919.13 Da        Isoelectric Point: 4.5802

>NTDB_id=201611 CG712_RS04185 WP_002951720.1 805107..805892(-) (codY) [Streptococcus thermophilus strain B59671]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide


Download         Length: 786 bp        

>NTDB_id=201611 CG712_RS04185 WP_002951720.1 805107..805892(-) (codY) [Streptococcus thermophilus strain B59671]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACGGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(201-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M305

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

64.591

98.467

0.636
  codY Bacillus subtilis subsp. subtilis str. 168

53.036

94.636

0.502

Multiple sequence alignment