Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CFN12_RS06370 Genome accession   NZ_CP022290
Coordinates   1238075..1238848 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain EDCC5458     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1233075..1243848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFN12_RS06350 (CFN12_06320) trmFO 1233419..1234726 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  CFN12_RS06355 (CFN12_06325) xerC 1235143..1236039 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  CFN12_RS06360 (CFN12_06330) hslV 1236036..1236581 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  CFN12_RS06365 (CFN12_06335) hslU 1236647..1238050 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  CFN12_RS06370 (CFN12_06340) codY 1238075..1238848 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CFN12_RS06375 (CFN12_06345) - 1238899..1238991 (+) 93 WP_001790530.1 hypothetical protein -
  CFN12_RS06380 (CFN12_06350) rpsB 1239190..1239957 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  CFN12_RS06385 (CFN12_06355) - 1239991..1240104 (+) 114 WP_001789890.1 hypothetical protein -
  CFN12_RS06390 (CFN12_06360) tsf 1240139..1241020 (+) 882 WP_000201387.1 translation elongation factor Ts -
  CFN12_RS06395 (CFN12_06365) pyrH 1241157..1241879 (+) 723 WP_000057330.1 UMP kinase -
  CFN12_RS06400 (CFN12_06370) frr 1241898..1242452 (+) 555 WP_001280006.1 ribosome recycling factor -
  CFN12_RS06405 (CFN12_06375) - 1242825..1243595 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=200211 CFN12_RS06370 WP_000055337.1 1238075..1238848(+) (codY) [Staphylococcus aureus strain EDCC5458]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=200211 CFN12_RS06370 WP_000055337.1 1238075..1238848(+) (codY) [Staphylococcus aureus strain EDCC5458]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment