Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   WH25_RS04665 Genome accession   NZ_CP017295
Coordinates   959909..960748 (+) Length   279 a.a.
NCBI ID   WP_046165840.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 954909..965748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS04640 (WH25_04640) tuf 955777..956973 (+) 1197 WP_045634647.1 elongation factor Tu -
  WH25_RS04645 (WH25_04645) tpiA 957244..958002 (+) 759 WP_005589685.1 triose-phosphate isomerase -
  WH25_RS04650 (WH25_04650) - 958130..958363 (+) 234 WP_037622338.1 DUF1146 family protein -
  WH25_RS04655 (WH25_04655) murA 958403..959683 (+) 1281 WP_012000226.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  WH25_RS04660 (WH25_04660) - 959676..959864 (+) 189 WP_020992673.1 DNA-directed RNA polymerase subunit beta -
  WH25_RS04665 (WH25_04665) endA 959909..960748 (+) 840 WP_046165840.1 DNA/RNA non-specific endonuclease Machinery gene
  WH25_RS04670 (WH25_04670) - 960964..961665 (-) 702 WP_046165839.1 alpha/beta hydrolase-fold protein -
  WH25_RS04675 (WH25_04675) - 961646..962674 (-) 1029 WP_046165838.1 ABC transporter substrate-binding protein -
  WH25_RS04680 (WH25_04680) - 962730..963485 (-) 756 WP_046165837.1 ABC transporter ATP-binding protein -
  WH25_RS04685 (WH25_04685) - 963487..964533 (-) 1047 WP_046165836.1 FecCD family ABC transporter permease -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30869.60 Da        Isoelectric Point: 10.0496

>NTDB_id=197414 WH25_RS04665 WP_046165840.1 959909..960748(+) (endA) [Streptococcus gordonii strain IE35]
MKKKQEEKLFQSIVGLILALVLIAGANYFSNHQNQDKIKSNPQVQRTGRRDISTPEQALSQSVLTDSVRKQLKGSIEWNQ
AGAYIINGNKTDLNADIASQPYAQNQTKSVQGQLVPIIGNALLSKQTRQYKNREETGNGTTSWVPAGWHQVRNLSGDFNH
AVDRGHLLAYSLVGGLKNFDASTSNPENIAVQTAWANQANSPSSTGQNFYESLIRKALDKKKRVRYRVTLIYANPDDLIA
VGSHLEAKSSDGSLEFNVFVPNIQTGIRINYRTGEVTVE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=197414 WH25_RS04665 WP_046165840.1 959909..960748(+) (endA) [Streptococcus gordonii strain IE35]
ATGAAGAAGAAACAAGAAGAGAAACTCTTTCAAAGTATAGTCGGACTGATTCTGGCACTTGTTCTGATAGCTGGTGCTAA
TTATTTCTCAAACCATCAGAATCAGGATAAGATAAAGTCTAATCCACAGGTTCAAAGAACAGGAAGAAGGGATATCTCAA
CTCCCGAGCAAGCACTATCTCAGAGTGTATTGACTGATTCTGTTCGCAAGCAATTAAAAGGCAGCATTGAATGGAATCAG
GCAGGTGCTTATATTATTAATGGCAACAAGACAGACCTGAATGCTGATATTGCCAGTCAGCCTTATGCACAAAATCAGAC
AAAGTCAGTTCAGGGACAGTTAGTACCAATAATTGGGAATGCTCTGCTTTCTAAACAGACTAGACAATACAAAAATCGAG
AAGAAACTGGAAACGGAACGACAAGTTGGGTTCCCGCCGGCTGGCATCAAGTAAGAAATCTTAGTGGAGATTTTAATCAT
GCAGTTGATCGAGGCCATTTATTAGCTTATTCTTTAGTCGGAGGCTTAAAGAACTTCGATGCTTCTACAAGTAACCCAGA
GAATATCGCTGTCCAAACAGCTTGGGCAAATCAGGCAAACAGTCCTTCATCTACTGGGCAAAATTTTTATGAAAGCTTGA
TTCGGAAGGCTTTGGATAAAAAGAAGCGAGTTCGTTATCGGGTAACCTTGATTTATGCTAATCCTGATGACTTGATAGCA
GTAGGCTCTCATTTGGAAGCAAAGTCCAGCGACGGAAGCCTCGAGTTTAATGTCTTCGTTCCGAATATTCAAACCGGGAT
TCGTATCAACTATAGAACTGGAGAAGTAACAGTAGAGTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(84-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.304

80.287

0.548
  endA Streptococcus pneumoniae D39

68.304

80.287

0.548
  endA Streptococcus pneumoniae R6

68.304

80.287

0.548
  endA Streptococcus pneumoniae TIGR4

68.304

80.287

0.548

Multiple sequence alignment