Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   A7J08_RS04180 Genome accession   NZ_CP017088
Coordinates   832470..833309 (+) Length   279 a.a.
NCBI ID   WP_053866841.1    Uniprot ID   A0A3S6K2W1
Organism   Streptococcus suis strain SRD478     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 827470..838309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS04150 (A7J08_04005) - 827935..828813 (+) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -
  A7J08_RS04155 (A7J08_04010) atpD 828833..830239 (+) 1407 WP_024407431.1 F0F1 ATP synthase subunit beta -
  A7J08_RS04160 (A7J08_04015) - 830249..830665 (+) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  A7J08_RS04165 (A7J08_04020) - 830725..830949 (+) 225 WP_012775178.1 DUF1146 family protein -
  A7J08_RS04170 (A7J08_04025) murA 830973..832256 (+) 1284 WP_053866840.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  A7J08_RS04175 (A7J08_04030) - 832249..832440 (+) 192 WP_012775177.1 DNA-directed RNA polymerase subunit beta -
  A7J08_RS04180 (A7J08_04035) endA 832470..833309 (+) 840 WP_053866841.1 DNA/RNA non-specific endonuclease Machinery gene
  A7J08_RS04185 (A7J08_04040) - 833496..835049 (+) 1554 WP_053866842.1 MFS transporter -
  A7J08_RS04190 (A7J08_04045) - 835105..836133 (+) 1029 WP_024400739.1 sugar kinase -
  A7J08_RS04195 (A7J08_04050) uidA 836149..837948 (+) 1800 WP_053866843.1 beta-glucuronidase -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30163.34 Da        Isoelectric Point: 6.2377

>NTDB_id=195402 A7J08_RS04180 WP_053866841.1 832470..833309(+) (endA) [Streptococcus suis strain SRD478]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVAEYSYYVNQSKASESTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQVHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDIVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=195402 A7J08_RS04180 WP_053866841.1 832470..833309(+) (endA) [Streptococcus suis strain SRD478]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTGGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGAATATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAGAGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGTGCT
GGAGCATTTATTATTAACGGGAATCAAACGGATTTAGATGCATCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
AACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCCAAATCTACACGTCAGTATAAGGACCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGGTCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGGCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGTTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCGGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACATTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S6K2W1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

70.339

84.588

0.595
  endA Streptococcus pneumoniae D39

70.339

84.588

0.595
  endA Streptococcus pneumoniae R6

70.339

84.588

0.595
  endA Streptococcus pneumoniae TIGR4

70.339

84.588

0.595

Multiple sequence alignment