Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   BFM96_RS06650 Genome accession   NZ_CP016953
Coordinates   1428938..1429777 (+) Length   279 a.a.
NCBI ID   WP_145939720.1    Uniprot ID   A0A917A6R6
Organism   Streptococcus himalayensis strain HTS2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1423938..1434777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS06615 - 1424047..1424694 (-) 648 WP_068991939.1 hemolysin III family protein -
  BFM96_RS06620 - 1424672..1425133 (-) 462 WP_068991942.1 DUF1836 domain-containing protein -
  BFM96_RS06625 yaaA 1425219..1425947 (+) 729 WP_068991945.1 peroxide stress protein YaaA -
  BFM96_RS06630 - 1425992..1426543 (-) 552 WP_068991947.1 NADPH-dependent FMN reductase -
  BFM96_RS06635 - 1426608..1427054 (-) 447 WP_068991950.1 MarR family winged helix-turn-helix transcriptional regulator -
  BFM96_RS10940 - 1427174..1427404 (+) 231 WP_083201813.1 DUF1146 family protein -
  BFM96_RS06640 murA 1427425..1428708 (+) 1284 WP_068991951.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  BFM96_RS06645 - 1428698..1428886 (+) 189 WP_068991954.1 DNA-directed RNA polymerase subunit beta -
  BFM96_RS06650 endA 1428938..1429777 (+) 840 WP_145939720.1 DNA/RNA non-specific endonuclease Machinery gene
  BFM96_RS06655 - 1429995..1431083 (+) 1089 WP_083201765.1 serine hydrolase -
  BFM96_RS06660 - 1431285..1432541 (-) 1257 WP_083201766.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30438.12 Da        Isoelectric Point: 10.0162

>NTDB_id=194048 BFM96_RS06650 WP_145939720.1 1428938..1429777(+) (endA) [Streptococcus himalayensis strain HTS2]
MAKYRGKKGKQTLVGLLLSLVLAAGGYYIGDQGGLVNQSAHQSQVEASYAPSRELAESVLTETVQQQLKGKIEWNGAGAF
VVNGNKTSVNANVASQPYADNKVKIVNGQLLPTVANSLMTKATRQYKKREETGNGSTNWTPAGWHQLRNLSGEYTHAVDR
GHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANKSNSTGQNFYESQVRRALDQNKRVRYRVTLLYQTEQDLVPAGSH
LEAKSSDGSLEFNVFIPNVQKGIVLNYQTGEVRLAPDIQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=194048 BFM96_RS06650 WP_145939720.1 1428938..1429777(+) (endA) [Streptococcus himalayensis strain HTS2]
ATGGCAAAATATAGAGGAAAAAAAGGGAAGCAAACCTTAGTTGGCTTGCTCCTGAGCTTGGTTTTAGCAGCTGGGGGGTA
TTATATTGGTGACCAAGGAGGATTGGTTAACCAATCTGCCCACCAGTCACAGGTAGAGGCTAGCTATGCCCCGAGCCGAG
AATTGGCAGAAAGTGTGCTAACTGAAACAGTCCAACAGCAGCTCAAGGGAAAGATTGAATGGAATGGAGCAGGGGCATTT
GTCGTGAATGGGAACAAAACAAGCGTAAATGCCAACGTTGCCAGTCAACCTTATGCCGACAACAAGGTCAAAATAGTAAA
CGGACAACTACTTCCAACGGTGGCCAATAGCCTGATGACCAAAGCAACGCGTCAATATAAAAAACGAGAAGAAACGGGCA
ATGGCTCCACCAATTGGACTCCAGCTGGCTGGCACCAACTGAGAAATCTTTCAGGCGAATACACCCATGCTGTGGATCGT
GGGCATTTGCTGGGGTATGCACTGATTGGCAATCTCAAAGGATTTGATGCCTCAACCAGCAATCCTAAAAACATTGCTGT
GCAGACCGCTTGGGCCAATCAAGCGAACAAAAGTAACTCGACTGGACAAAATTTTTATGAAAGTCAGGTGAGAAGAGCGC
TGGATCAAAATAAACGTGTTCGCTATCGAGTAACCTTGCTCTACCAAACAGAGCAAGATCTGGTTCCTGCTGGGTCTCAT
CTGGAAGCTAAATCAAGCGATGGTAGTTTGGAGTTTAATGTCTTTATTCCTAATGTTCAAAAAGGGATTGTCCTCAATTA
TCAAACAGGAGAAGTGCGACTAGCTCCTGACATTCAATGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(78-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

66.667

96.774

0.645
  endA Streptococcus pneumoniae D39

66.667

96.774

0.645
  endA Streptococcus pneumoniae R6

66.667

96.774

0.645
  endA Streptococcus pneumoniae TIGR4

66.667

96.774

0.645

Multiple sequence alignment