Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   BE845_RS05115 Genome accession   NZ_CP016874
Coordinates   1159414..1161621 (+) Length   735 a.a.
NCBI ID   WP_011214846.1    Uniprot ID   Q5WYS3
Organism   Legionella pneumophila subsp. pneumophila strain FFI329     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1154414..1166621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BE845_RS05100 (BE845_05100) - 1154841..1155353 (+) 513 WP_011214849.1 pilus assembly protein -
  BE845_RS05105 (BE845_05105) - 1155366..1158875 (+) 3510 WP_011214848.1 pilus assembly protein -
  BE845_RS05110 (BE845_05110) pilE 1158887..1159336 (+) 450 WP_011214847.1 type IV pilin protein Machinery gene
  BE845_RS05115 (BE845_05115) comEC 1159414..1161621 (+) 2208 WP_011214846.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BE845_RS05120 (BE845_05120) - 1161647..1162954 (-) 1308 WP_011214845.1 tetratricopeptide repeat protein -
  BE845_RS05125 (BE845_05125) - 1163156..1163533 (-) 378 WP_011214844.1 hypothetical protein -
  BE845_RS05130 (BE845_05130) - 1163670..1164062 (+) 393 WP_011214843.1 hypothetical protein -
  BE845_RS05135 (BE845_05135) - 1164187..1166115 (+) 1929 WP_011214842.1 hypothetical protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83188.84 Da        Isoelectric Point: 9.7068

>NTDB_id=193205 BE845_RS05115 WP_011214846.1 1159414..1161621(+) (comEC) [Legionella pneumophila subsp. pneumophila strain FFI329]
MEIFCFLIGVLYAYTYNIYLTIAIPLLFYITPRYPIVLFFIAGCGFALIHQWIVSPKGMPETQVITQAQLEGTIASIPMQ
RPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPVLRAGQRWQLSVKLKKPRNFHNPGGFNYVSYLGARHIYWTGYIRYGNN
KLISNQPPSFSWLILREKIGDTLTKMAPNTETAGIIEALTLNVTHHISSDHWNLFRRTGTVHLFGISGEHIALVSGIFFI
VMRWIWSINYRCCLFLPANTIASIGGLLAALPYAFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLALQLSCLIGLMPLTLHWYSYGSINGFLANLFAIPLVSFLIVPLAL
MTMITSPFHWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSVTMMLAMTAGLFLRVLLPVKPFKHLAILWIILPL
FPPRTAIYPGEALINILDVGQGLAVAIQTQHHVLLYDTGDSYFQGSDLGQMAIIPFFRSIGIKTIDKIVISHPDKDHKGG
LNSLEKEMQVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIRESFNKKNNNSCILQVSNSAGRVLLTGDIEKAAEE
YLVRNYGSQLASEILVVPHHGSKTSSSYRFLLEVSPLYAIASLGFDNRFKFPHSKTLQSMKTLGIIFFRTDECGMAGIKL
PASGKINKPTCMQAE

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=193205 BE845_RS05115 WP_011214846.1 1159414..1161621(+) (comEC) [Legionella pneumophila subsp. pneumophila strain FFI329]
ATGGAAATTTTTTGCTTTTTAATAGGCGTACTTTATGCCTATACCTATAATATTTATCTGACTATTGCGATTCCTTTACT
CTTTTATATCACACCAAGATATCCGATTGTCCTGTTCTTCATCGCCGGGTGCGGCTTTGCCCTGATTCATCAGTGGATTG
TATCTCCCAAGGGCATGCCTGAGACGCAAGTAATCACTCAAGCCCAATTGGAAGGAACTATTGCTTCCATCCCCATGCAA
CGTCCTAACAAAACCCAATTCCATTTTGCAATTGAAAAAATTAATAATAACCCTGCTCAAGGCTTGATCCAATTAAACTG
GTATAACAAACCGCCTGTCTTACGAGCCGGTCAGAGATGGCAACTTTCAGTGAAACTAAAAAAACCTCGTAACTTCCACA
ACCCGGGAGGTTTTAATTATGTAAGTTACCTGGGGGCTCGTCATATCTATTGGACTGGCTATATTCGTTATGGGAATAAT
AAGCTAATTAGCAATCAACCCCCTTCTTTCAGTTGGTTAATACTACGTGAAAAAATTGGGGATACTTTGACAAAAATGGC
ACCGAATACAGAAACGGCAGGCATCATCGAAGCATTGACGTTAAATGTTACTCACCATATCAGTTCAGATCATTGGAATT
TGTTCCGAAGAACAGGAACGGTACATTTATTCGGAATTTCAGGAGAGCACATCGCTCTGGTCTCCGGCATTTTCTTTATC
GTGATGAGATGGATTTGGTCAATAAATTATCGATGCTGTTTGTTCTTACCGGCCAATACCATAGCGAGTATCGGTGGGCT
ACTGGCCGCCTTGCCCTATGCTTTTTTAGCCGGGTTTGAGCCTCCTGTACAACGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATAGGAAAACAACGTTTTACACCATGGCAAATATGGAGATATGCCTTATTTTTAGTCTTGTGTATTGAG
CCCCATGCCGTATTCCTGCAAGGTTTTTACTTTTCATTTCTTGCCGTGGCCTGTCTTCTATTGACTCATCAACGCTGGCC
ACTGAAAAATTATAAAAAAACACTGGCATTACAATTAAGCTGCCTCATTGGATTAATGCCCTTGACTCTCCATTGGTACT
CCTATGGTTCTATCAATGGATTTCTTGCCAATTTATTCGCCATACCTTTAGTCAGTTTTCTGATAGTGCCCTTGGCTTTA
ATGACTATGATAACGAGTCCATTTCATTGGTCCTGGATATTGATGAAACCATTGGCGTGGCTTGTTGCCCTGTTACTGCA
AGGACTAACGTATGTTGAGCAAATAGCCGGGATCAATATCACCTGGTCCATCACCTCGGTAACAATGATGCTCGCTATGA
CAGCAGGTTTGTTTTTAAGGGTATTATTACCTGTCAAGCCCTTCAAACACTTGGCTATCCTTTGGATTATCCTTCCCTTA
TTTCCGCCTCGTACTGCAATTTATCCAGGGGAAGCATTAATTAATATTTTGGACGTTGGGCAAGGACTTGCCGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGATACGGGAGATTCCTATTTTCAGGGAAGTGATTTAGGGCAAATGGCGATAA
TCCCCTTTTTCAGGTCAATTGGAATAAAAACAATTGACAAAATAGTAATAAGCCATCCCGATAAAGATCATAAGGGCGGA
TTAAATTCCCTTGAAAAAGAGATGCAAGTCAATCAACTAATAGTGAATGATCCCTATTTTTATAAACGTGGAAGTAATTG
TCATTCATACCCGCAATGGCAATGGGATGGGGTGAGTTTTCGTTTTTTACCCATCAGGGAATCTTTCAATAAAAAAAATA
ATAATTCTTGTATCTTACAGGTAAGTAATTCGGCTGGCAGGGTTTTGTTAACGGGAGATATTGAAAAAGCAGCGGAGGAG
TACCTGGTAAGAAACTACGGCAGTCAGCTGGCATCCGAAATTTTAGTTGTGCCTCATCATGGGAGCAAAACGTCTTCATC
CTATCGATTTTTGCTGGAAGTAAGCCCGCTTTATGCCATTGCATCTTTAGGATTTGATAATCGCTTCAAATTTCCACATT
CTAAAACTTTGCAAAGCATGAAAACATTAGGTATCATTTTTTTTAGAACAGACGAATGTGGAATGGCAGGAATCAAACTA
CCTGCGTCAGGTAAAATTAACAAACCAACCTGTATGCAGGCTGAATAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(199-464)

Domain of unknown function (DUF4131) (DUF4131)

(21-158)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-578)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5WYS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

97.956

99.864

0.978
  comEC Legionella pneumophila strain ERS1305867

96.19

100

0.962

Multiple sequence alignment