Detailed information NTG0192918

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A7U47_RS07785
• Genome accession: NZ_CP016858
• Coordinates: 1483504..1484391 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 1971.C01
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1478504..1489391

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7U47_RS07755 (A7U47_0097)	-	1479236..1479997 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
A7U47_RS07760 (A7U47_0098)	-	1480242..1480697 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A7U47_RS15715 (A7U47_04165)	-	1480819..1480920 (+)	102	WP_000731972.1	SE2200 family small protein	-
A7U47_RS07770 (A7U47_0099)	-	1480980..1482404 (-)	1425	WP_000953744.1	alkaline phosphatase	-
A7U47_RS07775 (A7U47_0100)	-	1482602..1482802 (+)	201	WP_000604728.1	hypothetical protein	-
A7U47_RS07780 (A7U47_0101)	braR	1482828..1483493 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A7U47_RS07785 (A7U47_0102)	braS	1483504..1484391 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A7U47_RS07790 (A7U47_0103)	-	1484499..1485254 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A7U47_RS07795 (A7U47_04170)	-	1485251..1487251 (+)	2001	WP_000776751.1	ABC transporter permease	-
A7U47_RS07800 (A7U47_04175)	-	1487910..1488023 (+)	114	WP_001791776.1	hypothetical protein	-
A7U47_RS07810 (A7U47_04185)	-	1488405..1488665 (+)	261	WP_001789910.1	hypothetical protein	-
A7U47_RS07815 (A7U47_0107)	-	1488675..1489172 (+)	498	WP_001065268.1	glutathione peroxidase	-
A7U47_RS07820 (A7U47_04190)	-	1489280..1489372 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=192918 A7U47_RS07785 WP_000143419.1 1483504..1484391(+) (braS) [Staphylococcus aureus strain 1971.C01]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=192918 A7U47_RS07785 WP_000143419.1 1483504..1484391(+) (braS) [Staphylococcus aureus strain 1971.C01]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997