Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   A6L49_RS05090 Genome accession   NZ_CP016646
Coordinates   975609..977870 (-) Length   753 a.a.
NCBI ID   WP_002258690.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22819     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 970609..982870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L49_RS05075 (A6L49_05075) - 970628..971470 (-) 843 WP_002222980.1 class II glutamine amidotransferase -
  A6L49_RS05080 (A6L49_05080) aroB 972760..973839 (-) 1080 WP_002214528.1 3-dehydroquinate synthase -
  A6L49_RS05085 (A6L49_05085) - 973919..974431 (-) 513 WP_002222978.1 shikimate kinase -
  A6L49_RS05090 (A6L49_05090) pilQ 975609..977870 (-) 2262 WP_002258690.1 type IV pilus secretin PilQ Machinery gene
  A6L49_RS05095 (A6L49_05095) pilP 977889..978434 (-) 546 WP_002214522.1 pilus assembly protein PilP Machinery gene
  A6L49_RS05100 (A6L49_05100) - 978452..979099 (-) 648 WP_002217908.1 type 4a pilus biogenesis protein PilO -
  A6L49_RS05105 (A6L49_05105) pilN 979100..979699 (-) 600 WP_002217907.1 PilN domain-containing protein Machinery gene
  A6L49_RS05110 (A6L49_05110) pilM 979702..980817 (-) 1116 WP_065826102.1 type IV pilus biogenesis protein PilM -

Sequence

Protein


Download         Length: 753 a.a.        Molecular weight: 80941.36 Da        Isoelectric Point: 10.0237

>NTDB_id=190027 A6L49_RS05090 WP_002258690.1 975609..977870(-) (pilQ) [Neisseria meningitidis strain M22819]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQ
HDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGV
NNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIA
PRDELLAKDKALLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLISGRGSVLIDPATNTLIVTDTR
SVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPI
TAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGL
TVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIG
NLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2262 bp        

>NTDB_id=190027 A6L49_RS05090 WP_002258690.1 975609..977870(-) (pilQ) [Neisseria meningitidis strain M22819]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAAACCAATATCGATT
TCCGCAAAGACGGCAAAAATGCCGGCATTATCGAATTGGCTGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAG
CACGACCACATCATCGTTACGCTGAAAAACCATACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGCAGACTTTAA
AACACCGGTTCAAAAGGTTACGCTGAAACGCCTCAATAACGACACCCAGCTGATTATCACAACAGCCGGCAACTGGGAAC
TCGTCAACAAATCCGCCGCGCCCGGATACTTTACCTTCCAAGTCCTGCCGAAAAAACAAAACCTCGAGTCAGGCGGCGTG
AACAATGCGCCCAAAACCTTCACAGGCCGGAAAATCTCCCTTGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGAT
TTTGGCAAAAGAATCCGGAATGAACATTGTTGCCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAGGATGTGC
CTTGGGATCAGGCTTTGGATTTGGTTATGCAGGCGCGCAACCTCGATATGCGCCAGCAAGGGAATATCGTCAACATCGCG
CCCCGCGACGAGCTGCTTGCCAAAGACAAAGCCCTCTTACAGGCAGAAAAAGACATTGCCGATTTGGGTGCGCTGTATTC
CCAAAACTTCCAGTTGAAATACAAAAATGTGGAAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACACGACCGGAA
ACCGCAACACGCTTATCAGCGGCAGGGGCAGCGTGCTGATCGATCCCGCCACCAACACCCTGATTGTTACCGACACCCGC
AGCGTCATCGAAAAATTCCGCAAACTGATTGACGAATTGGACGTACCCGCGCAACAAGTGATGATTGAGGCGCGTATCGT
CGAAGCGGCAGACGGCTTCTCGCGCGATTTGGGCGTTAAATTCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAA
GCGCATTCGGCTGGGGGGTAAACTCCGGCTTCGGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATT
ACCGCTGCCGCAAACAGCATTTCGCTGGTGCGCGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATC
GCTTTCAAAAACCAAAACGCTTGCCAATCCGCGCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCCGGTTACG
AAATTCCTTTCACCGTAACCTCAATCGCGAACGGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTCTTGGGGCTG
ACCGTTACGCCGAACATCACGCCCGACGGCCAAATCATTATGACCGTCAAAATCAACAAGGACTCGCCTGCGCAATGTGC
CTCCGGTAATCAGACGATCCTGTGTATTTCGACCAAAAACCTGAATACGCAGGCTATGGTTGAAAACGGCGGCACATTGA
TTGTCGGCGGTATTTATGAAGAAGACAACGGCAATACGCTGACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGC
AACCTCTTTAAAACACGCGGGAAAAAAACCGACCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGC
CGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Secretin and TonB N terminus short domain (STN)

(355-400)

Bacterial type II/III secretion system short domain (Secretin_N)

(428-499)

Bacterial type II and III secretion system protein (Secretin)

(585-744)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

97.919

100

1
  pilQ Neisseria meningitidis M1080

98.423

100

0.995
  pilQ Neisseria gonorrhoeae strain FA1090

91.633

100

0.916

Multiple sequence alignment