Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   A6J72_RS07740 Genome accession   NZ_CP020433
Coordinates   1548498..1549286 (+) Length   262 a.a.
NCBI ID   WP_003035535.1    Uniprot ID   I0SFK2
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1543498..1554286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS07720 (A6J72_07710) - 1544056..1545018 (-) 963 WP_082312148.1 asparaginase -
  A6J72_RS07725 (A6J72_07715) - 1545083..1546471 (+) 1389 WP_082312149.1 Cof-type HAD-IIB family hydrolase -
  A6J72_RS07730 (A6J72_07720) - 1546517..1546969 (-) 453 WP_003028799.1 universal stress protein -
  A6J72_RS07735 (A6J72_07725) - 1547122..1548336 (+) 1215 WP_003074453.1 pyridoxal phosphate-dependent aminotransferase -
  A6J72_RS07740 (A6J72_07730) codY 1548498..1549286 (+) 789 WP_003035535.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  A6J72_RS07745 (A6J72_07735) - 1549286..1549861 (+) 576 WP_082312150.1 cysteine hydrolase family protein -
  A6J72_RS07750 (A6J72_07740) aspS 1550241..1551989 (+) 1749 WP_082312151.1 aspartate--tRNA ligase -
  A6J72_RS07755 (A6J72_07745) gatC 1552054..1552356 (+) 303 WP_082312152.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  A6J72_RS07760 (A6J72_07750) gatA 1552356..1553822 (+) 1467 WP_082312153.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29724.06 Da        Isoelectric Point: 5.0797

>NTDB_id=186459 A6J72_RS07740 WP_003035535.1 1548498..1549286(+) (codY) [Streptococcus intermedius strain FDAARGOS_233]
MANLLAKTRKITSILRRSDERLQDELPYNAITQQLAEIMDCNACIVNSKGRLLGYFMRYKTNNDRVEAFYQTKIFPEEYV
RTANLMYDTEANLPVNHDLSIFPIETKDEFPDGLTTISPIHVSGIRLGTLIVWRNDKEFDDDDLILVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELSGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLIPDIFEEIKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=186459 A6J72_RS07740 WP_003035535.1 1548498..1549286(+) (codY) [Streptococcus intermedius strain FDAARGOS_233]
ATGGCAAACTTATTAGCAAAAACAAGAAAAATAACATCTATTTTGCGTCGTTCAGATGAGCGATTGCAGGATGAACTACC
TTATAATGCAATTACCCAACAATTAGCTGAAATTATGGATTGCAATGCTTGTATTGTAAATAGCAAGGGTCGTCTTTTGG
GGTATTTCATGCGCTACAAGACAAACAATGATCGTGTGGAAGCATTTTATCAAACGAAAATCTTCCCAGAAGAGTATGTT
CGCACCGCAAATTTGATGTATGATACTGAGGCCAATCTTCCAGTCAATCATGATTTATCTATTTTTCCTATTGAGACAAA
AGATGAATTTCCAGATGGCTTGACGACAATTTCACCAATTCATGTTTCTGGGATTCGTTTAGGGACATTGATTGTTTGGC
GCAATGATAAAGAATTTGACGATGATGATTTGATCTTGGTTGAAATTGCAAGTACAGTGGTTGGTATTCAGCTACTCAAC
TTCCAACGAGAAGAAGATGAAAAAAATATTCGACGTCGAACAGCTGTAACTATGGCTGTAAATACTTTGTCTTATTCAGA
ATTACGAGCTGTTTCTGCTATTTTAGGTGAATTAAGCGGCAATGAAGGGCAGCTAACAGCTTCAGTGATTGCAGATCGTA
TTGGCATTACGCGCTCAGTGATTGTCAATGCTCTACGTAAACTAGAAAGTGCAGGCATTATCGAAAGTCGTTCTCTAGGA
ATGAAAGGAACCTATCTTAAAGTTCTTATCCCTGATATCTTTGAAGAGATTAAAAAGCGAGATTACTGA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SFK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

61.832

100

0.618
  codY Bacillus subtilis subsp. subtilis str. 168

50

93.893

0.469