Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   B5D85_RS00675 Genome accession   NZ_CP020082
Coordinates   104860..105144 (+) Length   94 a.a.
NCBI ID   WP_307777288.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB120304     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99860..110144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B5D85_RS00650 (B5D85_00650) - 101806..102171 (+) 366 WP_002986560.1 DUF1033 family protein -
  B5D85_RS00655 (B5D85_00655) comGA 102264..103202 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  B5D85_RS00660 (B5D85_00660) comGB 103138..104172 (+) 1035 WP_228631569.1 competence type IV pilus assembly protein ComGB Machinery gene
  B5D85_RS00665 (B5D85_00665) comGC 104174..104500 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  B5D85_RS00670 (B5D85_00670) comGD 104475..104903 (+) 429 WP_076639399.1 competence type IV pilus minor pilin ComGD Machinery gene
  B5D85_RS00675 (B5D85_00675) comGE 104860..105144 (+) 285 WP_307777288.1 competence type IV pilus minor pilin ComGE Machinery gene
  B5D85_RS00680 (B5D85_00680) comGF 105137..105571 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  B5D85_RS00685 (B5D85_00685) comGG 105555..105881 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  B5D85_RS00690 (B5D85_00690) comGH 105979..106932 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  B5D85_RS00695 (B5D85_00695) - 106991..108187 (+) 1197 WP_020904834.1 acetate kinase -
  B5D85_RS00700 (B5D85_00700) - 108374..108682 (+) 309 Protein_89 hypothetical protein -
  B5D85_RS00705 (B5D85_00705) proC 108765..109535 (-) 771 WP_076639397.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10700.68 Da        Isoelectric Point: 8.9043

>NTDB_id=184554 B5D85_RS00675 WP_307777288.1 104860..105144(+) (comGE) [Streptococcus pyogenes strain STAB120304]
MGIIKKQVKAYIVLESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=184554 B5D85_RS00675 WP_307777288.1 104860..105144(+) (comGE) [Streptococcus pyogenes strain STAB120304]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGTCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAT
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383