Detailed information NTG0182229

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: B1761_RS03665
• Genome accession: NZ_CP019935
• Coordinates: 691496..692281 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain APC151
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 686496..697281

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B1761_RS03630 (B1761_03660)	gatC	686558..686860 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
B1761_RS03635 (B1761_03665)	-	687000..687254 (-)	255	WP_024010053.1	glycosyl transferase	-
B1761_RS03640 (B1761_03670)	-	687267..687476 (-)	210	WP_080998437.1	glycosyltransferase	-
B1761_RS03645 (B1761_03675)	-	687792..689236 (-)	1445	Protein_692	6-phospho-beta-glucosidase	-
B1761_RS03650 (B1761_03680)	msrA	689389..689898 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
B1761_RS03655 (B1761_03685)	-	689910..690758 (-)	849	WP_014608646.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
B1761_RS03660 (B1761_03690)	-	690882..691433 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
B1761_RS03665 (B1761_03695)	codY	691496..692281 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
B1761_RS03670 (B1761_03700)	-	692541..693755 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
B1761_RS03675 (B1761_03705)	-	694110..694562 (+)	453	WP_002946987.1	universal stress protein	-
B1761_RS03680 (B1761_03710)	-	694742..695313 (+)	572	Protein_699	IS30 family transposase	-
B1761_RS10260	-	695385..695558 (-)	174	WP_011681546.1	hypothetical protein	-
B1761_RS03685 (B1761_03715)	-	695619..695993 (-)	375	WP_011681547.1	membrane protein	-
B1761_RS03690 (B1761_03720)	pflA	696205..697005 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=182229 B1761_RS03665 WP_002951720.1 691496..692281(-) (codY) [Streptococcus thermophilus strain APC151]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=182229 B1761_RS03665 WP_002951720.1 691496..692281(-) (codY) [Streptococcus thermophilus strain APC151]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502