Detailed information NTG0178321

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: V471_RS08360
• Genome accession: NZ_CP015283
• Coordinates: 1785938..1786819 (-)
• Length: 293 a.a.
• NCBI ID: WP_048790587.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1780938..1791819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS08330 (V471_08215)	-	1781323..1782021 (+)	699	WP_084871394.1	amino acid ABC transporter permease	-
V471_RS08335 (V471_08220)	-	1782033..1782683 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
V471_RS08340 (V471_08225)	-	1782870..1783637 (+)	768	WP_084871395.1	amino acid ABC transporter ATP-binding protein	-
V471_RS08345 (V471_08230)	-	1783649..1784482 (+)	834	WP_084871396.1	transporter substrate-binding domain-containing protein	-
V471_RS08350 (V471_08235)	-	1784500..1785198 (+)	699	WP_084871397.1	amino acid ABC transporter permease	-
V471_RS08355 (V471_08240)	-	1785210..1785860 (+)	651	WP_037601175.1	amino acid ABC transporter permease	-
V471_RS08360 (V471_08245)	endA	1785938..1786819 (-)	882	WP_048790587.1	DNA/RNA non-specific endonuclease	Machinery gene
V471_RS08365 (V471_08250)	-	1786881..1787069 (-)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-
V471_RS08370 (V471_08255)	murA	1787071..1788342 (-)	1272	WP_084871398.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V471_RS08375 (V471_08260)	-	1788410..1788646 (-)	237	WP_002890830.1	DUF1146 family protein	-
V471_RS08380 (V471_08265)	-	1788968..1790071 (-)	1104	WP_013990687.1	glycosyl hydrolase family 8	-
V471_RS08385 (V471_08270)	-	1790080..1791390 (-)	1311	WP_014633211.1	glycosyltransferase family 2 protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31518.14 Da
• Isoelectric Point: 10.2036

>NTDB_id=178321 V471_RS08360 WP_048790587.1 1785938..1786819(-) (endA) [Streptococcus salivarius strain ATCC 25975]
MAKRKTSLTNKQKRQLVSLLIAVLIAVLGYIGTSNKLSPNNPIKQVASLVSGKSNNSVKSNGSTNGKATPQEQLAESVMT
TSVKSQLGNSLEWNGAGAYIVNGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVHNLSGEYSHAVDRGHLLGYALVGGLKGFDASTSNPENIAVQTAWANQANSESSTGQNYYESLVRKAQDKNKRVR
YRVTLIYEGDNLIPSGSHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=178321 V471_RS08360 WP_048790587.1 1785938..1786819(-) (endA) [Streptococcus salivarius strain ATCC 25975]
ATGGCAAAAAGAAAGACATCTTTAACAAATAAACAGAAACGTCAGCTAGTCTCGTTACTAATAGCGGTCTTGATTGCAGT
TTTAGGTTACATTGGGACGAGCAATAAGCTATCGCCTAATAATCCAATCAAGCAGGTAGCTAGTCTAGTCTCGGGAAAAT
CCAATAACTCCGTTAAATCAAACGGTTCAACAAATGGAAAGGCTACGCCACAAGAGCAGCTTGCTGAGTCAGTGATGACT
ACCTCCGTCAAGAGTCAACTAGGAAACTCCTTAGAATGGAATGGGGCAGGGGCTTATATTGTTAATGGTAATAAGACTAA
TCTAAATGCTAAGGTTTCTAGCCAACCCTATGCCAATAACCAAGTCAAAACGGTTCAAGGACAAACGGTTCCTACAGTAG
CGAATGCCTTATTAAGTAAAGCAACCAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGCTCAACCTCTTGGACACCT
GCGGGATGGCATCAAGTTCACAATCTTTCAGGAGAGTATAGCCATGCCGTAGATAGAGGTCATTTGTTGGGCTATGCACT
TGTAGGTGGTCTCAAAGGATTTGATGCCTCGACTTCAAATCCAGAAAATATTGCCGTTCAAACTGCTTGGGCTAACCAAG
CTAATAGCGAAAGTTCTACGGGACAAAACTATTATGAAAGCCTGGTAAGAAAAGCTCAGGATAAAAACAAACGTGTCCGT
TATCGCGTTACCCTTATTTATGAAGGGGATAACCTCATTCCATCAGGATCACATCTTGAAGCCAAGTCAGCTGATGGCTC
ACTTGAGTTCAATGTCTTTGTTCCAAATGTACAAGAAGGGATTACCCTAGATTATTATTCAGGAAAAGTAACTGTGAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	71.542	86.348	0.618
endA	Streptococcus pneumoniae D39	71.542	86.348	0.618
endA	Streptococcus pneumoniae R6	71.542	86.348	0.618
endA	Streptococcus pneumoniae TIGR4	71.542	86.348	0.618