Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   BtBc_RS19865 Genome accession   NZ_CP015150
Coordinates   3952603..3953382 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus thuringiensis strain Bc601     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3937157..3994828 3952603..3953382 within 0


Gene organization within MGE regions


Location: 3937157..3994828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BtBc_RS19810 (BtBc_19810) rimP 3938059..3938529 (-) 471 WP_000359096.1 ribosome maturation factor RimP -
  BtBc_RS19815 (BtBc_19815) - 3938866..3943167 (-) 4302 WP_000060004.1 PolC-type DNA polymerase III -
  BtBc_RS19820 (BtBc_19820) - 3943292..3944992 (-) 1701 WP_000814333.1 proline--tRNA ligase -
  BtBc_RS19825 (BtBc_19825) rseP 3945102..3946358 (-) 1257 WP_001090245.1 RIP metalloprotease RseP -
  BtBc_RS19830 (BtBc_19830) dxr 3946376..3947518 (-) 1143 WP_000790372.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  BtBc_RS19835 (BtBc_19835) cdsA 3947542..3948333 (-) 792 WP_000813592.1 phosphatidate cytidylyltransferase -
  BtBc_RS19840 (BtBc_19840) uppS 3948351..3949127 (-) 777 WP_000971296.1 isoprenyl transferase -
  BtBc_RS19845 (BtBc_19845) frr 3949213..3949770 (-) 558 WP_000531501.1 ribosome recycling factor -
  BtBc_RS19850 (BtBc_19850) pyrH 3949773..3950495 (-) 723 WP_000042668.1 UMP kinase -
  BtBc_RS19855 (BtBc_19855) tsf 3950562..3951449 (-) 888 WP_001018578.1 translation elongation factor Ts -
  BtBc_RS19860 (BtBc_19860) rpsB 3951553..3952254 (-) 702 WP_000111485.1 30S ribosomal protein S2 -
  BtBc_RS19865 (BtBc_19865) codY 3952603..3953382 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  BtBc_RS19870 (BtBc_19870) hslU 3953460..3954851 (-) 1392 WP_000550087.1 ATP-dependent protease ATPase subunit HslU -
  BtBc_RS19875 (BtBc_19875) hslV 3954874..3955416 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  BtBc_RS19880 (BtBc_19880) xerC 3955459..3956358 (-) 900 WP_001101241.1 tyrosine recombinase XerC -
  BtBc_RS19885 (BtBc_19885) trmFO 3956424..3957728 (-) 1305 WP_000213002.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  BtBc_RS19890 (BtBc_19890) topA 3957777..3959855 (-) 2079 WP_001286963.1 type I DNA topoisomerase -
  BtBc_RS19895 (BtBc_19895) dprA 3960000..3960869 (-) 870 WP_000818039.1 DNA-processing protein DprA -
  BtBc_RS19900 (BtBc_19900) sucD 3960957..3961859 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  BtBc_RS19905 (BtBc_19905) sucC 3961879..3963039 (-) 1161 WP_001020791.1 ADP-forming succinate--CoA ligase subunit beta -
  BtBc_RS19910 (BtBc_19910) - 3963234..3964007 (-) 774 WP_001193513.1 ribonuclease HII -
  BtBc_RS19915 (BtBc_19915) ylqF 3964064..3964954 (-) 891 WP_000236702.1 ribosome biogenesis GTPase YlqF -
  BtBc_RS19920 (BtBc_19920) lepB 3964975..3965526 (-) 552 WP_000711851.1 signal peptidase I -
  BtBc_RS19925 (BtBc_19925) rplS 3965628..3965972 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  BtBc_RS19930 (BtBc_19930) trmD 3966119..3966853 (-) 735 WP_000686903.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BtBc_RS19935 (BtBc_19935) rimM 3966853..3967368 (-) 516 WP_000170278.1 ribosome maturation factor RimM -
  BtBc_RS19940 (BtBc_19940) - 3967489..3967716 (-) 228 WP_000737401.1 KH domain-containing protein -
  BtBc_RS19945 (BtBc_19945) rpsP 3967731..3968003 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  BtBc_RS19950 (BtBc_19950) ffh 3968105..3969454 (-) 1350 WP_000863460.1 signal recognition particle protein -
  BtBc_RS19955 (BtBc_19955) - 3969467..3969799 (-) 333 WP_000891062.1 putative DNA-binding protein -
  BtBc_RS19960 (BtBc_19960) ftsY 3969933..3970922 (-) 990 WP_000007655.1 signal recognition particle-docking protein FtsY -
  BtBc_RS19965 (BtBc_19965) smc 3970938..3974045 (-) 3108 Protein_3963 chromosome segregation protein SMC -
  BtBc_RS19970 (BtBc_19970) ltrA 3974143..3975948 (-) 1806 WP_000108316.1 group II intron reverse transcriptase/maturase -
  BtBc_RS19975 (BtBc_19975) - 3976652..3977113 (-) 462 Protein_3965 AAA family ATPase -
  BtBc_RS19980 (BtBc_19980) rncS 3977260..3977997 (-) 738 WP_001146875.1 ribonuclease III -
  BtBc_RS19985 (BtBc_19985) acpP 3978056..3978289 (-) 234 WP_000786062.1 acyl carrier protein -
  BtBc_RS19990 (BtBc_19990) fabG 3978359..3979099 (-) 741 WP_000911768.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  BtBc_RS19995 (BtBc_19995) fabD 3979099..3980043 (-) 945 WP_000515905.1 ACP S-malonyltransferase -
  BtBc_RS20000 (BtBc_20000) plsX 3980058..3981050 (-) 993 WP_000684098.1 phosphate acyltransferase PlsX -
  BtBc_RS20005 (BtBc_20005) fapR 3981047..3981640 (-) 594 WP_000747349.1 transcription factor FapR -
  BtBc_RS20010 (BtBc_20010) recG 3981729..3983777 (-) 2049 WP_001000811.1 ATP-dependent DNA helicase RecG -
  BtBc_RS20015 (BtBc_20015) - 3984068..3985744 (-) 1677 WP_000027129.1 DAK2 domain-containing protein -
  BtBc_RS20020 (BtBc_20020) - 3985767..3986129 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  BtBc_RS20025 (BtBc_20025) rpmB 3986506..3986694 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  BtBc_RS20030 (BtBc_20030) spoVM 3986768..3986848 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  BtBc_RS20035 (BtBc_20035) - 3986915..3987595 (-) 681 WP_002132739.1 thiamine diphosphokinase -
  BtBc_RS20040 (BtBc_20040) rpe 3987665..3988309 (-) 645 WP_000589974.1 ribulose-phosphate 3-epimerase -
  BtBc_RS20045 (BtBc_20045) rsgA 3988312..3989193 (-) 882 WP_001113932.1 ribosome small subunit-dependent GTPase A -
  BtBc_RS20050 (BtBc_20050) pknB 3989440..3991413 (-) 1974 WP_000904748.1 Stk1 family PASTA domain-containing Ser/Thr kinase -
  BtBc_RS20055 (BtBc_20055) - 3991422..3992174 (-) 753 WP_000648703.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BtBc_RS20060 (BtBc_20060) rlmN 3992179..3993267 (-) 1089 WP_000450541.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  BtBc_RS20065 (BtBc_20065) rsmB 3993272..3994606 (-) 1335 WP_001249668.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=177148 BtBc_RS19865 WP_000421290.1 3952603..3953382(-) (codY) [Bacillus thuringiensis strain Bc601]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=177148 BtBc_RS19865 WP_000421290.1 3952603..3953382(-) (codY) [Bacillus thuringiensis strain Bc601]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGGAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCAAACGTATTCGTAGTTAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAAAACGAACGCATGAAGCAAATGCTTGCAGAACGTCAATTCCCAGAAGAATATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTGAACAGTGCTTACACAGCATTCCCAGTAGAAAACAGAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCGAT
TGAGCACATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCTGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment