Detailed information NTG0176348

Bioinformatically predicted

Overview

• Name: priA
• Type: Machinery gene
• Locus tag: BUM80_RS06035
• Genome accession: NZ_CP018838
• Coordinates: 1128771..1131167 (-)
• Length: 798 a.a.
• NCBI ID: WP_001152101.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 11A
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1123771..1136167

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS06015 (BUM80_06205)	stkP	1123786..1125765 (-)	1980	WP_000614535.1	serine/threonine-protein kinase StkP	Regulator
BUM80_RS06020 (BUM80_06210)	-	1125762..1126502 (-)	741	WP_000406247.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
BUM80_RS06025 (BUM80_06215)	rsmB	1126517..1127830 (-)	1314	WP_001810150.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
BUM80_RS06030 (BUM80_06220)	fmt	1127823..1128758 (-)	936	WP_000163705.1	methionyl-tRNA formyltransferase	-
BUM80_RS06035 (BUM80_06225)	priA	1128771..1131167 (-)	2397	WP_001152101.1	primosomal protein N'	Machinery gene
BUM80_RS06040 (BUM80_06230)	rpoZ	1131233..1131547 (-)	315	WP_000979235.1	DNA-directed RNA polymerase subunit omega	-
BUM80_RS06045 (BUM80_06235)	gmk	1131572..1132198 (-)	627	WP_000775037.1	guanylate kinase	-
BUM80_RS06050 (BUM80_06240)	-	1132328..1133941 (-)	1614	WP_000404929.1	ribonuclease Y	-
BUM80_RS06055 (BUM80_06245)	-	1134132..1134386 (-)	255	WP_000924721.1	Txe/YoeB family addiction module toxin	-
BUM80_RS06060 (BUM80_06250)	-	1134390..1134644 (-)	255	WP_000388572.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
BUM80_RS06065 (BUM80_06255)	-	1134882..1135979 (-)	1098	WP_061823230.1	nucleotidyltransferase	-

Sequence

Protein

• Length: 798 a.a.
• Molecular weight: 90032.79 Da
• Isoelectric Point: 6.1261

>NTDB_id=176348 BUM80_RS06035 WP_001152101.1 1128771..1131167(-) (priA) [Streptococcus pneumoniae strain 11A]
MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKGNRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPV
LTPEQLWLAEELRKSVFSYKISILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLASLLESYSREQVNFFVDQGAVTIV
QKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSSIGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEIS
LTPQMTERFIARFGDKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYKQESNPRYH
AREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLATIPEVQVIDFRDYIGQNETSNFTPPLLEAIQ
DRLVKKEQVVLMLNRRGYSSFVMCRECGTVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQ
KVYDELAELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGVLNADTALNLPDFRSSE
RTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDYEGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKR
AYEVMNILRSGLSETSPILGPTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL

Nucleotide

• Length: 2397 bp

>NTDB_id=176348 BUM80_RS06035 WP_001152101.1 1128771..1131167(-) (priA) [Streptococcus pneumoniae strain 11A]
ATGGCCCTAGCTAAGATTATCGTAGATGTGCCCTTGATGCAGACGGACCAGCCCTATAGTTACAGGATTCCGGAGGAATT
TGAGGGAATGCTGGAAGTTGGGATGCGGGTTCATGTGCCTTTTGGTAAGGGTAATCGCCTGATTCAAGGGATTGTTCTTG
GTTTGGAGTCCCAATCAGATGGAGAAGAGATGGAGCAAGATTTAAAAGATATTGCAGAGGTGCTGGATTTTTCTCCTGTT
CTCACGCCAGAACAACTCTGGCTGGCTGAGGAGTTACGCAAATCTGTCTTCTCCTACAAAATCTCTATCCTCAAGGCCAT
GCTTCCGGGATTTCTGAATTCTAGCTATGACAAGATTCTCTATCCTCTGGAAGGCTTGAGTCAGGAAGAACGAGTACGCC
TGTTTGGTTCAGAAGATTCGCTAGCCTTTTCTTCTCTGGATTTAGGTAAGCAAGCTGAAATGATGCGTTTGACTAGAAAA
GGCCTGCTTGGTCTGGAATATCAGGCAGTCGATCAAAAGAAGGTCAAGACCCAGTCTTGGTATGAGGTTGACCATGCTCA
ATTAGAAGGTGTTGAGATTTCTACACGTGCCAAGAAAAAGTTGGAACTGAGAGATTATCTGCTGTCTCATCCAGAGAGCG
CTTCCTTGGCTAGCTTGTTGGAGTCCTACTCGCGAGAGCAAGTCAACTTCTTTGTGGATCAAGGTGCTGTTACCATAGTC
CAAAAGGAAGTTCAACGCTCGGCTGCTTATTTTGAAGGAATTGAAGCAAGTAGACCTTTGGAGTTAAATCCAGAACAAAG
ACAGGCGCGTGATGCGGTTGTGAGTTCTATTGGCAGTTCTCAACCTCCCTTTCTACTTCAAGGGATTACAGGAAGTGGGA
AGACCGAGGTTTACTTGCAGATTATCCAAGGTGCCCTGGATAAGGGCAAGACAGCTATTTTGCTGGTACCTGAGATTTCC
TTGACTCCTCAAATGACCGAGCGTTTTATAGCACGCTTTGGGGACAAGGTAGCCATTCTTCACTCAGGATTATCCAATGG
TGAAAAGTATGATGAATGGCGCAAGGTGGAGCGTGGCGATGCCCAAGTTGTTGTTGGTGCCAGATCTGCTATCTTTGCTC
CTCTGAAAAATCTGGGTGTCATGATTATTGATGAAGAGCATGAAGCGGCTTATAAGCAGGAAAGCAATCCCCGTTACCAT
GCCAGAGAGGTAGCTATTTTACGGGCTCAGTATAATCAAGCAACTCTGGTACTTGGATCTGCAACGCCGAGCTTAGAGAG
CCGGGCGCGTGCTGGCAAAGGCGTCTATCAACACTTACGTCTAACCCAACGTGCCAATCCTTTGGCTACAATCCCTGAGG
TTCAAGTGATTGACTTTCGAGACTATATCGGACAAAATGAGACGTCAAACTTTACGCCTCCTTTGCTAGAGGCTATCCAA
GACCGTCTGGTTAAAAAAGAGCAGGTGGTTCTCATGCTCAATCGCCGTGGTTATTCTAGCTTTGTCATGTGTCGGGAGTG
TGGGACGGTGGATACTTGTCCCAACTGCGATATTTCTCTGACCTTGCATATGGATACCAAGACTATGAACTGCCATTATT
GTGGTTTCTCGAAGGATATTCCTCAGGTCTGTCCTAACTGTAAGAGCCACAGTATTCGTTACTATGGGACGGGAACTCAG
AAGGTTTATGATGAGCTAGCAGAACTCTTTCCCCAAGCTCGCATTCTGAGGATGGATGTGGATACGACTCGAAAGAAAGG
CAGTCACCAAGCCTTGCTTGACCAGTTTGGGCGAGGGGAAGCGGATATTTTACTTGGTACTCAGATGATTGCAAAGGGTT
TGGATTTTCCCAATGTTACCCTAGTCGGAGTTCTAAATGCGGATACGGCCTTGAATCTGCCTGATTTCCGTTCTTCTGAG
AGAACCTTCCAGCTCTTGACTCAGGTGGCAGGTCGAGCAGGTCGGGCTGAAAAGGCAGGTCAAGTCTTGATACAGTCCTA
CAATCCGCAGCACTATGCTATTCGATTTGCCAAGGATCAAGATTACGAAGGCTTTTATGCCTATGAAATGGGAATCAGAC
GACAACTCGGCTATCCACCTTACTATTTCACGATTGGTATTACCCTTTCTCACAAGAAAGAAGAAGAGGTTTTCAAACGT
GCCTATGAAGTCATGAACATTTTGCGGTCAGGCTTGTCAGAGACCAGTCCCATTCTGGGGCCAACGCCAAAACCGATTGC
CCGTACCCACAACCTCTATCATTACCAGATTTTAATTAAATACCGTTTAGAAGATGAGCTGGGGCCGACCCTCAACCAGG
TTTTAGCCTTGACTCAAGAACGGGAAAATAGTGAGCTCCGTCTCAGCATTGACCATGAGCCGCAGCAATTTTTATAA

Domains

Predicted by InterProScan.

• 3DNA-binding domain (3BD) (PriA_3primeBD) (5-109)

• PriA DNA helicase Cys-rich region (CRR) domain (Zn_ribbon_PriA) (513-538)

• Primosomal protein N C-terminal domain (PriA_C) (700-794)

• Helicase conserved C-terminal domain (Helicase_C) (570-656)

• Type III restriction enzyme, res subunit (ResIII) (260-424)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
priA	Bacillus subtilis subsp. subtilis str. 168	46.305	100	0.471