Detailed information NTG0175930

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PA1088_RS25785
• Genome accession: NZ_CP015001
• Coordinates: 5533593..5534930 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA1088
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5528593..5539930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA1088_RS25760 (PA1088_05151)	pgeF	5528736..5529464 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
PA1088_RS25765 (PA1088_05152)	rluD	5529461..5530423 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PA1088_RS25770 (PA1088_05153)	-	5530569..5531594 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PA1088_RS25775 (PA1088_05154)	-	5531751..5531996 (+)	246	WP_003102591.1	PP0621 family protein	-
PA1088_RS25780 (PA1088_05155)	pilS	5531986..5533578 (+)	1593	WP_003119425.1	two-component system sensor histidine kinase PilS	Regulator
PA1088_RS25785 (PA1088_05156)	pilR	5533593..5534930 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PA1088_RS25790 (PA1088_05157)	thiO	5534976..5536070 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
PA1088_RS25795 (PA1088_05158)	-	5536205..5536714 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
PA1088_RS25800 (PA1088_05159)	-	5536820..5537326 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
PA1088_RS25805 (PA1088_05160)	pilV	5537317..5537874 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
PA1088_RS25810 (PA1088_05161)	pilW	5537871..5538695 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
PA1088_RS25815 (PA1088_05162)	pilX	5538692..5539279 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=175930 PA1088_RS25785 WP_003094694.1 5533593..5534930(+) (pilR) [Pseudomonas aeruginosa strain PA1088]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=175930 PA1088_RS25785 WP_003094694.1 5533593..5534930(+) (pilR) [Pseudomonas aeruginosa strain PA1088]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384