Detailed information NTG0173769

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: BSR20_RS08375
• Genome accession: NZ_CP018189
• Coordinates: 1822251..1823036 (-)
• Length: 261 a.a.
• NCBI ID: WP_045772004.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC3
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1817251..1828036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR20_RS08345 (BSR20_08425)	gatC	1817647..1817949 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
BSR20_RS08350 (BSR20_08430)	-	1818089..1818529 (-)	441	Protein_1596	glycosyltransferase	-
BSR20_RS08355 (BSR20_08435)	-	1818550..1819989 (-)	1440	WP_045772000.1	6-phospho-beta-glucosidase	-
BSR20_RS08360 (BSR20_08440)	msrA	1820142..1820651 (-)	510	WP_045772001.1	peptide-methionine (S)-S-oxide reductase MsrA	-
BSR20_RS08365 (BSR20_08445)	-	1820663..1821511 (-)	849	WP_045772002.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
BSR20_RS08370 (BSR20_08450)	-	1821633..1822184 (-)	552	WP_045772003.1	cysteine hydrolase family protein	-
BSR20_RS08375 (BSR20_08455)	codY	1822251..1823036 (-)	786	WP_045772004.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
BSR20_RS08380 (BSR20_08460)	-	1823304..1824518 (-)	1215	WP_002884715.1	pyridoxal phosphate-dependent aminotransferase	-
BSR20_RS08385 (BSR20_08465)	-	1824882..1825334 (+)	453	WP_002891687.1	universal stress protein	-
BSR20_RS08390 (BSR20_08470)	-	1825413..1826165 (-)	753	WP_004183318.1	hypothetical protein	-
BSR20_RS08395 (BSR20_08475)	pflA	1826235..1827035 (-)	801	WP_156209931.1	pyruvate formate-lyase-activating protein	-
BSR20_RS08400 (BSR20_08480)	-	1827222..1827959 (-)	738	WP_149561188.1	LPXTG cell wall anchor domain-containing protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28816.85 Da
• Isoelectric Point: 4.3715

>NTDB_id=173769 BSR20_RS08375 WP_045772004.1 1822251..1823036(-) (codY) [Streptococcus salivarius strain ICDC3]
MANLLAKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNTDRVEEFFEAKQLPEEYT
RGISRVYDTQENIGIDSDLTIFPVESKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDEDLILVEIASTVVGLQLLN
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=173769 BSR20_RS08375 WP_045772004.1 1822251..1823036(-) (codY) [Streptococcus salivarius strain ICDC3]
ATGGCAAATTTGCTGGCTAAAACACGTAAAATTACATCTATCTTGCAACGCTCAGTAGATAGCTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAATTGGCGGATATCATTGATTGTAACGCTGCTATCGTTAATGGTGGTGGTGCTCTTCTTG
GTTTTGCCATGAAGTACAAAACCAACACTGATCGTGTGGAAGAGTTTTTTGAAGCCAAACAACTTCCAGAAGAATACACA
CGTGGTATCAGCCGTGTTTATGACACTCAAGAAAACATTGGTATTGACAGTGACTTGACCATTTTCCCTGTGGAGTCAAA
AGATGACTTCCCAGATGGTTTGACTACAATTGCACCTATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATCATTTGGC
GTAACGATCATGACTTTGTAGATGAAGATCTTATCTTGGTTGAAATTGCCTCTACAGTAGTTGGGTTGCAGTTGTTGAAC
CTTCAAACAGAGAACTTGGAAGAAACAATTCGTAAACAAACAGCTATCAACATGGCAATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTGGAAGGTCGCTTGACAGCGTCTGTTATCGCTGACCGTA
TTGGAATTACACGTTCAGTTATCGTTAATGCCCTTCGTAAGTTGGAATCAGCTGGTATTATTGAGAGCCGTTCACTCGGT
ATGAAAGGGACTTATCTTAAAGTCCTTAACGAAGGTATCTACGATAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	52.632	94.636	0.498