Detailed information NTG0173545

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: BSR14_RS08370
• Genome accession: NZ_CP018186
• Coordinates: 1822256..1823041 (-)
• Length: 261 a.a.
• NCBI ID: WP_045772004.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC1
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1817256..1828041

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR14_RS08340 (BSR14_08420)	gatC	1817652..1817954 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
BSR14_RS08345 (BSR14_08425)	-	1818094..1818534 (-)	441	Protein_1599	glycosyltransferase	-
BSR14_RS08350 (BSR14_08430)	-	1818555..1819994 (-)	1440	WP_045772000.1	6-phospho-beta-glucosidase	-
BSR14_RS08355 (BSR14_08435)	msrA	1820147..1820656 (-)	510	WP_045772001.1	peptide-methionine (S)-S-oxide reductase MsrA	-
BSR14_RS08360 (BSR14_08440)	-	1820668..1821516 (-)	849	WP_045772002.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
BSR14_RS08365 (BSR14_08445)	-	1821638..1822189 (-)	552	WP_045772003.1	cysteine hydrolase family protein	-
BSR14_RS08370 (BSR14_08450)	codY	1822256..1823041 (-)	786	WP_045772004.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
BSR14_RS08375 (BSR14_08455)	-	1823309..1824523 (-)	1215	WP_002884715.1	pyridoxal phosphate-dependent aminotransferase	-
BSR14_RS08380 (BSR14_08460)	-	1824887..1825339 (+)	453	WP_002891687.1	universal stress protein	-
BSR14_RS08385 (BSR14_08465)	-	1825418..1826170 (-)	753	WP_004183318.1	hypothetical protein	-
BSR14_RS08390 (BSR14_08470)	pflA	1826240..1827040 (-)	801	WP_156209931.1	pyruvate formate-lyase-activating protein	-
BSR14_RS08395 (BSR14_08475)	-	1827227..1827964 (-)	738	WP_149561188.1	LPXTG cell wall anchor domain-containing protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28816.85 Da
• Isoelectric Point: 4.3715

>NTDB_id=173545 BSR14_RS08370 WP_045772004.1 1822256..1823041(-) (codY) [Streptococcus salivarius strain ICDC1]
MANLLAKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNTDRVEEFFEAKQLPEEYT
RGISRVYDTQENIGIDSDLTIFPVESKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDEDLILVEIASTVVGLQLLN
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=173545 BSR14_RS08370 WP_045772004.1 1822256..1823041(-) (codY) [Streptococcus salivarius strain ICDC1]
ATGGCAAATTTGCTGGCTAAAACACGTAAAATTACATCTATCTTGCAACGCTCAGTAGATAGCTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAATTGGCGGATATCATTGATTGTAACGCTGCTATCGTTAATGGTGGTGGTGCTCTTCTTG
GTTTTGCCATGAAGTACAAAACCAACACTGATCGTGTGGAAGAGTTTTTTGAAGCCAAACAACTTCCAGAAGAATACACA
CGTGGTATCAGCCGTGTTTATGACACTCAAGAAAACATTGGTATTGACAGTGACTTGACCATTTTCCCTGTGGAGTCAAA
AGATGACTTCCCAGATGGTTTGACTACAATTGCACCTATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATCATTTGGC
GTAACGATCATGACTTTGTAGATGAAGATCTTATCTTGGTTGAAATTGCCTCTACAGTAGTTGGGTTGCAGTTGTTGAAC
CTTCAAACAGAGAACTTGGAAGAAACAATTCGTAAACAAACAGCTATCAACATGGCAATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTGGAAGGTCGCTTGACAGCGTCTGTTATCGCTGACCGTA
TTGGAATTACACGTTCAGTTATCGTTAATGCCCTTCGTAAGTTGGAATCAGCTGGTATTATTGAGAGCCGTTCACTCGGT
ATGAAAGGGACTTATCTTAAAGTCCTTAACGAAGGTATCTACGATAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	52.632	94.636	0.498