Detailed information NTG0173350

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A0O21_RS04505
• Genome accession: NZ_CP014699
• Coordinates: 965502..966344 (+)
• Length: 280 a.a.
• NCBI ID: WP_067061958.1
• Uniprot ID: A0A172Q7E2
• Organism: Streptococcus pantholopis strain TA 26
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 960502..971344

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A0O21_RS04480 (A0O21_04485)	ylqF	960912..961766 (+)	855	WP_067061944.1	ribosome biogenesis GTPase YlqF	-
A0O21_RS04485 (A0O21_04490)	-	961753..962532 (+)	780	WP_067061947.1	ribonuclease HII	-
A0O21_RS04490 (A0O21_04495)	-	962529..963515 (+)	987	WP_067061950.1	YdcF family protein	-
A0O21_RS04495 (A0O21_04500)	-	963636..964628 (+)	993	WP_067061952.1	ROK family protein	-
A0O21_RS04500 (A0O21_04505)	-	964813..965031 (+)	219	Protein_899	iron chelate uptake ABC transporter family permease subunit	-
A0O21_RS04505 (A0O21_04510)	dprA	965502..966344 (+)	843	WP_067061958.1	DNA-processing protein DprA	Machinery gene
A0O21_RS04510 (A0O21_04515)	topA	966437..968560 (+)	2124	WP_067061962.1	type I DNA topoisomerase	-
A0O21_RS04515 (A0O21_04520)	trmFO	968823..970157 (+)	1335	WP_067061965.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
A0O21_RS04520 (A0O21_04525)	-	970651..971136 (-)	486	WP_067061968.1	PASTA domain-containing protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 30872.73 Da
• Isoelectric Point: 9.2427

>NTDB_id=173350 A0O21_RS04505 WP_067061958.1 965502..966344(+) (dprA) [Streptococcus pantholopis strain TA 26]
MNNFELFKLKQAGLSNLNVINILTYQKQKQKSLSLRDMAVVSQCKDPLLFIEAYKNLNSKELRPVFNRFPSVSILDKAYP
LELKSVYNPPVLLYYSGNLDLLTKPKLAVVGGRLASDIGTKSIQKIIKELNNHFVIISGLARGIDTSAHLACLKNGGSTI
AVIGTGLNVTYPKENAQLQQYISKNHLALTEYDPDSPPLRFHFPERNRIIAGLAQGVIVAEAKRRSGSLITCERALEEGR
DVFAVPGNILDGKSDGCLHLIQEGAKCITSGFDVVSEYQL

Nucleotide

• Length: 843 bp

>NTDB_id=173350 A0O21_RS04505 WP_067061958.1 965502..966344(+) (dprA) [Streptococcus pantholopis strain TA 26]
ATGAATAATTTTGAACTTTTCAAACTGAAACAGGCAGGACTCAGCAATCTCAATGTTATTAACATTTTGACTTACCAGAA
ACAGAAGCAGAAATCATTGTCCTTACGTGATATGGCTGTAGTATCTCAGTGTAAAGATCCTCTTTTATTTATTGAAGCCT
ACAAAAATTTAAACAGTAAGGAACTAAGACCTGTTTTTAATCGTTTCCCGTCGGTTTCCATATTGGATAAGGCTTACCCT
TTAGAACTGAAATCTGTGTATAATCCGCCGGTTTTGCTATATTATTCTGGAAATCTGGATTTGCTGACTAAGCCTAAATT
AGCAGTAGTTGGAGGACGTTTGGCGTCTGATATCGGTACAAAGTCTATTCAAAAAATTATCAAAGAGCTTAATAATCATT
TTGTTATTATCAGCGGTTTAGCGCGTGGTATTGATACAAGTGCACATCTGGCCTGCTTAAAAAACGGAGGCAGTACAATT
GCTGTTATCGGAACAGGATTAAATGTTACATACCCAAAAGAAAATGCACAGCTTCAGCAGTATATCAGCAAAAATCATTT
GGCTTTGACAGAGTATGATCCCGATTCTCCACCTTTAAGATTTCATTTTCCTGAGAGAAACCGGATTATTGCAGGTTTAG
CACAAGGGGTTATCGTAGCAGAAGCTAAAAGGCGTTCAGGCAGCCTGATTACTTGTGAAAGAGCGTTGGAAGAAGGGAGA
GATGTCTTTGCTGTTCCCGGCAATATTTTAGATGGAAAATCAGATGGCTGTCTTCATTTAATTCAAGAGGGAGCAAAGTG
TATTACAAGTGGGTTTGATGTTGTTTCCGAGTACCAATTATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A172Q7E2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.5	100	0.725
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.286	100	0.593
dprA/cilB/dalA	Streptococcus mitis SK321	59.286	100	0.593
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	58.929	100	0.589
dprA/cilB/dalA	Streptococcus pneumoniae R6	58.929	100	0.589
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	58.929	100	0.589
dprA/cilB/dalA	Streptococcus pneumoniae D39	58.929	100	0.589
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	99.286	0.564