Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AXE83_RS09095 Genome accession   NZ_CP014264
Coordinates   1953332..1954162 (-) Length   276 a.a.
NCBI ID   WP_060956212.1    Uniprot ID   A0AAJ2T5K0
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1948332..1959162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS09085 (AXE83_09085) - 1950313..1951569 (-) 1257 WP_037612702.1 ISL3 family transposase -
  AXE83_RS09090 (AXE83_09090) - 1951748..1953079 (-) 1332 WP_060956211.1 hemolysin family protein -
  AXE83_RS09095 (AXE83_09095) endA 1953332..1954162 (-) 831 WP_060956212.1 DNA/RNA non-specific endonuclease Machinery gene
  AXE83_RS09100 (AXE83_09100) - 1954528..1954716 (-) 189 WP_060956404.1 DNA-directed RNA polymerase subunit beta -
  AXE83_RS09105 (AXE83_09105) murA 1954709..1955995 (-) 1287 WP_000411899.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AXE83_RS09110 (AXE83_09110) - 1956021..1956251 (-) 231 WP_000615324.1 DUF1146 family protein -
  AXE83_RS09115 (AXE83_09115) sepM 1956308..1957345 (-) 1038 WP_000730764.1 SepM family pheromone-processing serine protease Regulator
  AXE83_RS09120 (AXE83_09120) coaD 1957329..1957817 (-) 489 WP_049529746.1 pantetheine-phosphate adenylyltransferase -
  AXE83_RS09125 (AXE83_09125) rsmD 1957807..1958346 (-) 540 WP_049502925.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -

Sequence

Protein


Download         Length: 276 a.a.        Molecular weight: 30212.73 Da        Isoelectric Point: 9.7187

>NTDB_id=170024 AXE83_RS09095 WP_060956212.1 1953332..1954162(-) (endA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MNKKTRQALIGLLLFLLLSAGSYYIKQMQSSNTAPQTQVKQKSQSSDTPSQELAESVLTDSVKKQIKGTLEWNSAGAFIV
NNNKTNLDAKVSSKPYADNKTKTVGGETVPTVANAIMSKATRQYKDREETGNGSTSWTPAGWHQVKNLKGSYNHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQARAEDSTGQNYYESLVRKALDQNKRVRYRVTLLYASEEDLVPSASQIE
AKSSDGELEFNVVIPNVQKGIQLDYRTGEVTVTKNS

Nucleotide


Download         Length: 831 bp        

>NTDB_id=170024 AXE83_RS09095 WP_060956212.1 1953332..1954162(-) (endA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGAATAAAAAAACAAGGCAGGCCCTAATTGGTCTCTTGCTCTTTTTGCTCTTGTCAGCAGGAAGCTACTATATTAAACA
AATGCAGTCTTCCAACACTGCACCACAAACACAAGTAAAACAAAAATCACAGTCGTCTGATACTCCAAGTCAAGAACTGG
CTGAAAGTGTATTGACCGATTCAGTTAAAAAACAAATTAAGGGTACTCTAGAGTGGAATAGCGCAGGAGCCTTTATCGTC
AATAACAATAAAACCAATCTAGACGCCAAGGTTTCAAGTAAACCCTATGCGGATAATAAAACAAAGACTGTAGGAGGAGA
GACGGTTCCCACAGTAGCGAATGCAATCATGTCAAAAGCGACCAGACAGTACAAGGATCGTGAAGAAACTGGCAATGGTT
CAACATCTTGGACGCCTGCGGGTTGGCATCAGGTTAAGAATCTAAAGGGAAGTTACAACCATGCGGTCGATAGAGGGCAT
TTGTTGGGCTATGCCTTAATCGGTGGTTTAGATGGCTTTGATGCTTCTACTAGCAATCCTAAAAACATTGCCGTACAGAC
GGCTTGGGCCAACCAAGCGCGTGCAGAAGATTCGACAGGTCAAAACTACTATGAGAGCTTGGTTCGAAAAGCCCTAGATC
AGAATAAACGAGTGCGTTACCGTGTGACGTTGCTCTATGCGTCTGAGGAAGACTTGGTGCCGTCCGCATCGCAGATTGAA
GCCAAGTCCTCTGATGGGGAGTTGGAGTTTAATGTCGTTATTCCAAATGTCCAAAAGGGAATTCAGTTAGATTACCGAAC
AGGTGAGGTCACAGTCACAAAAAATAGCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

85.401

99.275

0.848
  endA Streptococcus pneumoniae D39

85.401

99.275

0.848
  endA Streptococcus pneumoniae R6

85.401

99.275

0.848
  endA Streptococcus pneumoniae TIGR4

85.401

99.275

0.848

Multiple sequence alignment