Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   A7J08_RS00890 Genome accession   NZ_CP017088
Coordinates   145098..146048 (+) Length   316 a.a.
NCBI ID   WP_053867353.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 140098..151048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS00880 (A7J08_00875) - 143507..143881 (+) 375 WP_024385120.1 DUF1033 family protein -
  A7J08_RS00885 (A7J08_00880) - 143915..144826 (-) 912 Protein_136 S66 peptidase family protein -
  A7J08_RS00890 (A7J08_00885) comGA 145098..146048 (+) 951 WP_053867353.1 competence type IV pilus ATPase ComGA Machinery gene
  A7J08_RS00895 (A7J08_00890) comGB 145960..146997 (+) 1038 WP_238600014.1 competence type IV pilus assembly protein ComGB Machinery gene
  A7J08_RS00900 (A7J08_00895) comGC 146999..147280 (+) 282 WP_053866667.1 competence type IV pilus major pilin ComGC Machinery gene
  A7J08_RS00905 (A7J08_00900) comGD 147261..147668 (+) 408 WP_053866668.1 competence type IV pilus minor pilin ComGD Machinery gene
  A7J08_RS00910 (A7J08_00905) comGE 147640..147933 (+) 294 WP_053866669.1 competence type IV pilus minor pilin ComGE Machinery gene
  A7J08_RS00915 (A7J08_00910) comGF/cglF 147920..148354 (+) 435 WP_053866670.1 competence type IV pilus minor pilin ComGF Machinery gene
  A7J08_RS00920 (A7J08_00915) comGG 148332..148745 (+) 414 WP_053866671.1 competence type IV pilus minor pilin ComGG -
  A7J08_RS00925 (A7J08_00920) comGH 148795..149748 (+) 954 WP_053866672.1 class I SAM-dependent methyltransferase Machinery gene
  A7J08_RS00930 (A7J08_00925) - 149798..150985 (+) 1188 WP_053866673.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35414.29 Da        Isoelectric Point: 5.2913

>NTDB_id=165983 A7J08_RS00890 WP_053867353.1 145098..146048(+) (comGA) [Streptococcus suis strain SRD478]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDMAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNEQIDCLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=165983 A7J08_RS00890 WP_053867353.1 145098..146048(+) (comGA) [Streptococcus suis strain SRD478]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAGGAGGCGGTGGCAGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGGCTATCAAGTCTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACATGGCTGAGGAAGAAGTAATAGCCA
TTATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGGGATTATCGTGGTAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTAATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGAGTCTAT
GCCCGTATGTTAGAACTAGGTGTCAGCCCCGAGGAGTTAAATAATGCCCTTCAAGGGATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGAACAAATTGATTGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comGA Streptococcus mutans UA159

67.524

98.418

0.665
  comGA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538

Multiple sequence alignment