Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   A7J08_RS00390 Genome accession   NZ_CP017088
Coordinates   68719..70656 (+) Length   645 a.a.
NCBI ID   WP_053866700.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 63719..75656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS00370 - 64190..65480 (+) 1291 Protein_54 IS4 family transposase -
  A7J08_RS00375 (A7J08_00380) - 65667..66887 (+) 1221 WP_079739207.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  A7J08_RS00385 (A7J08_00390) - 67078..68601 (+) 1524 WP_053866699.1 quinol oxidase -
  A7J08_RS00390 (A7J08_00395) hexB 68719..70656 (+) 1938 WP_053866700.1 DNA mismatch repair endonuclease MutL Machinery gene
  A7J08_RS00395 (A7J08_00400) ruvA 70695..71285 (+) 591 WP_053866701.1 Holliday junction branch migration protein RuvA Machinery gene
  A7J08_RS00400 (A7J08_00405) - 71296..71865 (+) 570 WP_053866702.1 DNA-3-methyladenine glycosylase I -
  A7J08_RS00405 (A7J08_00410) cinA 71902..73083 (+) 1182 WP_148115621.1 competence/damage-inducible protein A Machinery gene
  A7J08_RS00410 (A7J08_00415) recA 73135..74286 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  A7J08_RS00415 (A7J08_00420) spx 74522..74920 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  A7J08_RS00420 (A7J08_00425) - 75020..75286 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72883.12 Da        Isoelectric Point: 5.2344

>NTDB_id=165975 A7J08_RS00390 WP_053866700.1 68719..70656(+) (hexB) [Streptococcus suis strain SRD478]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMVIETATADSTHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLKEPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQKHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=165975 A7J08_RS00390 WP_053866700.1 68719..70656(+) (hexB) [Streptococcus suis strain SRD478]
ATGTCACATATTATTGAACTACCAGAAATATTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTTCCTTCCATTGCTTCTGTCAG
TCATATGGTTATTGAGACAGCTACGGCAGACTCTACACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCCGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCGTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTTAATCGAGC
GATTTTGGAAGGTTATGGTAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCGGTGATTTCTATTGAGATTGATCCTTATT
TGGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAAAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCGACATCCGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGAAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CATATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCATATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAAGAGATTGAGTCTGGTATTTATGAGATGTGCGACATGTTGCTTTTG
ACGGATCAGGTGTCTATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAATTGGGGAAATATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.615

100

0.732

Multiple sequence alignment