Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ATM98_RS00095 Genome accession   NZ_CP013651
Coordinates   19031..20329 (+) Length   432 a.a.
NCBI ID   WP_061563643.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 14031..25329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS00070 (ATM98_00070) - 14822..15454 (+) 633 WP_061563639.1 response regulator transcription factor -
  ATM98_RS00075 (ATM98_00075) - 15499..16905 (+) 1407 WP_061563640.1 Cof-type HAD-IIB family hydrolase -
  ATM98_RS00080 (ATM98_00080) - 16902..17270 (+) 369 WP_048715304.1 S1 RNA-binding domain-containing protein -
  ATM98_RS00085 (ATM98_00085) cysK 17322..18251 (-) 930 WP_061563641.1 cysteine synthase A -
  ATM98_RS00090 (ATM98_00090) - 18343..18975 (-) 633 WP_061563642.1 YigZ family protein -
  ATM98_RS00095 (ATM98_00095) comFA/cflA 19031..20329 (+) 1299 WP_061563643.1 DEAD/DEAH box helicase Machinery gene
  ATM98_RS00100 (ATM98_00100) - 20326..20997 (+) 672 WP_061563644.1 ComF family protein -
  ATM98_RS00105 (ATM98_00105) raiA 21085..21630 (+) 546 WP_006596830.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49728.18 Da        Isoelectric Point: 9.5553

>NTDB_id=163383 ATM98_RS00095 WP_061563643.1 19031..20329(+) (comFA/cflA) [Streptococcus sp. A12]
MKLEDCYGRLFTQDQLEDDLLEQAQQLPAIVQEKTGLTCNRCGTKIDKARWKLQIGSYYCRACIQLGRVRSDQTLYYFPQ
QAFPQEEVLRWQGTLTPFQSRVSQELVQSLTERKPMMVHAVTGAGKTEMMYQVVAEMIKKGRCVCIATPRIDVCIELYKR
MTLDFSCPISLLHGDSDPYFRTPLVISTTHQLLKFYQAFDLLIIDEVDAFPFVDNPVLYHAVSNAVTKNGKLIYLTATST
EELDKKVKKQEIKRVSLPRRFHGNPLVVPKKVWLKDLRKKIEKKQVPTKLLKLIKEQRKTSFPLILFVSEIELGEKILSL
LRRAFKNEIIELVTSKTDNRLELVEKFRNQEITILVSTTILERGVTFPKVDVFVIEANHRLFTKSALVQIAGRVGRSMER
PTGELLYLAEGSSKEMTQAIKEIKEMNREAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=163383 ATM98_RS00095 WP_061563643.1 19031..20329(+) (comFA/cflA) [Streptococcus sp. A12]
ATGAAACTTGAAGATTGTTATGGACGCTTGTTCACCCAAGACCAACTGGAGGATGACCTGCTTGAGCAGGCTCAGCAACT
ACCAGCTATAGTGCAGGAAAAGACGGGTTTGACTTGTAATCGGTGCGGAACCAAGATTGATAAGGCTAGATGGAAACTAC
AGATAGGAAGCTACTATTGTAGAGCCTGCATTCAATTGGGAAGAGTTAGAAGTGACCAAACACTTTATTATTTTCCCCAA
CAAGCCTTTCCGCAAGAAGAAGTCTTAAGATGGCAGGGGACCTTAACGCCTTTTCAAAGTCGGGTTTCCCAGGAGTTGGT
TCAATCCTTAACAGAAAGGAAGCCAATGATGGTACACGCGGTAACAGGAGCAGGTAAAACGGAAATGATGTACCAAGTGG
TGGCGGAAATGATTAAAAAAGGGAGATGTGTATGCATTGCTACACCAAGGATTGACGTGTGTATTGAATTGTATAAACGG
ATGACGCTGGACTTTTCCTGTCCCATCTCCTTGTTGCACGGTGACTCAGACCCTTATTTCCGAACGCCTCTTGTCATATC
CACTACTCATCAACTACTCAAATTTTATCAAGCTTTCGATCTCCTCATAATCGATGAAGTCGATGCCTTTCCTTTTGTTG
ACAACCCCGTTCTCTATCATGCCGTTTCAAATGCCGTAACCAAGAATGGGAAGCTCATCTATTTGACAGCTACCTCCACA
GAAGAATTGGATAAAAAGGTCAAAAAACAGGAGATAAAACGCGTTAGTCTACCTAGACGCTTTCATGGTAATCCCCTTGT
GGTCCCTAAAAAAGTATGGTTAAAAGATCTACGTAAAAAAATAGAAAAGAAACAAGTGCCAACGAAGTTGCTCAAGCTAA
TAAAAGAACAACGGAAAACCTCCTTTCCCCTGATCCTATTTGTATCAGAAATCGAATTAGGAGAAAAAATCCTCAGTCTA
TTAAGAAGGGCCTTCAAGAATGAGATCATCGAACTGGTAACCTCAAAAACGGATAATAGGTTGGAACTGGTAGAAAAATT
TCGCAATCAAGAAATCACTATACTTGTGTCAACGACCATTCTCGAACGGGGGGTCACCTTCCCTAAAGTAGACGTGTTTG
TGATTGAGGCCAACCATCGATTGTTTACCAAGAGCGCTCTGGTTCAAATCGCAGGTCGTGTGGGAAGAAGTATGGAAAGA
CCCACAGGGGAATTACTATACTTGGCAGAAGGTAGTAGCAAAGAGATGACGCAAGCTATTAAAGAAATAAAAGAAATGAA
TCGGGAGGCAGGTTTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-396)

Type III restriction enzyme, res subunit (ResIII)

(95-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

61.201

100

0.613
  comFA/cflA Streptococcus pneumoniae D39

61.449

99.074

0.609
  comFA/cflA Streptococcus pneumoniae R6

61.449

99.074

0.609
  comFA/cflA Streptococcus pneumoniae TIGR4

61.449

99.074

0.609
  comFA/cflA Streptococcus pneumoniae Rx1

61.449

99.074

0.609
  comFA/cflA Streptococcus mitis SK321

60.739

100

0.609
  comFA Lactococcus lactis subsp. cremoris KW2

53.299

91.204

0.486
  comFA Latilactobacillus sakei subsp. sakei 23K

37.731

100

0.377

Multiple sequence alignment