Detailed information NTG0161114

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ATC05_RS15675
• Genome accession: NZ_CP013245
• Coordinates: 3399059..3400396 (-)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain VA-134
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 3394059..3405396

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATC05_RS15645 (ATC05_15635)	pilX	3394710..3395297 (-)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-
ATC05_RS15650 (ATC05_15640)	pilW	3395294..3396118 (-)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ATC05_RS15655 (ATC05_15645)	pilV	3396115..3396672 (-)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ATC05_RS15660 (ATC05_15650)	-	3396663..3397169 (-)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ATC05_RS15665 (ATC05_15655)	-	3397275..3397784 (-)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
ATC05_RS15670 (ATC05_15660)	thiO	3397919..3399013 (+)	1095	WP_003119424.1	glycine oxidase ThiO	-
ATC05_RS15675 (ATC05_15665)	pilR	3399059..3400396 (-)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ATC05_RS15680 (ATC05_15670)	pilS	3400411..3402003 (-)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ATC05_RS15685 (ATC05_15675)	-	3401993..3402238 (-)	246	WP_003102591.1	PP0621 family protein	-
ATC05_RS15690 (ATC05_15680)	-	3402395..3403420 (-)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ATC05_RS15695 (ATC05_15685)	rluD	3403566..3404528 (+)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ATC05_RS15700 (ATC05_15690)	pgeF	3404525..3405253 (+)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=161114 ATC05_RS15675 WP_003094694.1 3399059..3400396(-) (pilR) [Pseudomonas aeruginosa strain VA-134]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=161114 ATC05_RS15675 WP_003094694.1 3399059..3400396(-) (pilR) [Pseudomonas aeruginosa strain VA-134]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384