Detailed information NTG0160548

Bioinformatically predicted

Overview

• Name: comGH
• Type: Machinery gene
• Locus tag: BBP08_RS08175
• Genome accession: NZ_CP016501
• Coordinates: 1610450..1611424 (-)
• Length: 324 a.a.
• NCBI ID: WP_001008574.1
• Uniprot ID: Q8E232
• Organism: Streptococcus agalactiae strain WC1535
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1605450..1616424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BBP08_RS08140 (BBP08_07860)	pepA	1605513..1606580 (+)	1068	WP_001281323.1	glutamyl aminopeptidase	-
BBP08_RS08145 (BBP08_07865)	proC	1606650..1607420 (+)	771	WP_001865901.1	pyrroline-5-carboxylate reductase	-
BBP08_RS08150 (BBP08_07870)	-	1607441..1608106 (-)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-
BBP08_RS08155 (BBP08_07875)	-	1608175..1608630 (-)	456	WP_000905673.1	hypothetical protein	-
BBP08_RS11640 (BBP08_11620)	-	1608671..1608799 (-)	129	WP_014959723.1	hypothetical protein	-
BBP08_RS08165 (BBP08_07880)	-	1608867..1609073 (-)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
BBP08_RS08170 (BBP08_07885)	-	1609225..1610418 (-)	1194	WP_000047534.1	acetate kinase	-
BBP08_RS08175 (BBP08_07890)	comGH	1610450..1611424 (-)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
BBP08_RS08180 (BBP08_07895)	comGG	1611539..1611910 (-)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
BBP08_RS08185 (BBP08_07900)	comGF	1611888..1612343 (-)	456	WP_000793378.1	competence type IV pilus minor pilin ComGF	Machinery gene
BBP08_RS08190 (BBP08_07905)	comGB	1612340..1613383 (-)	1044	Protein_1541	competence type IV pilus assembly protein ComGB	-
BBP08_RS08195 (BBP08_07910)	comGA	1613277..1614248 (-)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
BBP08_RS08205 (BBP08_07915)	-	1614421..1614786 (-)	366	WP_000285373.1	DUF1033 family protein	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 37046.02 Da
• Isoelectric Point: 4.5224

>NTDB_id=160548 BBP08_RS08175 WP_001008574.1 1610450..1611424(-) (comGH) [Streptococcus agalactiae strain WC1535]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK

Nucleotide

• Length: 975 bp

>NTDB_id=160548 BBP08_RS08175 WP_001008574.1 1610450..1611424(-) (comGH) [Streptococcus agalactiae strain WC1535]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG

Domains

Predicted by InterProScan.

• N-6 DNA Methylase (N6_Mtase) (70-303)

3D structure

• AlphaFold DB: Q8E232

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGH	Streptococcus mutans UA159	67.302	97.222	0.654
comGH	Streptococcus mutans UA140	67.302	97.222	0.654