Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AMM49_RS04690 Genome accession   NZ_CP012480
Coordinates   894776..895633 (+) Length   285 a.a.
NCBI ID   WP_000163017.1    Uniprot ID   A0AB38VM19
Organism   Streptococcus agalactiae strain NGBS128     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 889776..900633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMM49_RS04660 (AMM49_04655) - 890092..890973 (+) 882 WP_000919083.1 F0F1 ATP synthase subunit gamma -
  AMM49_RS04665 (AMM49_04660) atpD 891047..892453 (+) 1407 WP_000094375.1 F0F1 ATP synthase subunit beta -
  AMM49_RS04670 (AMM49_04665) - 892466..892879 (+) 414 WP_000068055.1 F0F1 ATP synthase subunit epsilon -
  AMM49_RS04675 (AMM49_04670) - 892944..893174 (+) 231 WP_000602601.1 DUF1146 family protein -
  AMM49_RS04680 (AMM49_04675) murA 893237..894508 (+) 1272 WP_000357880.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AMM49_RS04685 (AMM49_04680) - 894510..894701 (+) 192 WP_000168511.1 DNA-directed RNA polymerase subunit beta -
  AMM49_RS04690 (AMM49_04685) endA 894776..895633 (+) 858 WP_000163017.1 DNA/RNA non-specific endonuclease Machinery gene
  AMM49_RS04695 (AMM49_04690) pheS 895924..896964 (+) 1041 WP_000365655.1 phenylalanine--tRNA ligase subunit alpha -
  AMM49_RS04700 (AMM49_04695) - 897047..897567 (+) 521 Protein_838 GNAT family N-acetyltransferase -
  AMM49_RS04705 (AMM49_04700) pheT 897621..900026 (+) 2406 WP_000961583.1 phenylalanine--tRNA ligase subunit beta -

Sequence

Protein


Download         Length: 285 a.a.        Molecular weight: 31366.37 Da        Isoelectric Point: 10.4835

>NTDB_id=154601 AMM49_RS04690 WP_000163017.1 894776..895633(+) (endA) [Streptococcus agalactiae strain NGBS128]
MTKKQKQITASIVTLLFSLLAIGLGESKSLPNDHILKQVTDLIISNESGKNTSLKNISGTPSRELSESVLTSNVKKQLGT
NIAWNQSGAFIINQNKTDLNAKVSSAPYAINEIKKVNNQIVPTKANALLTKATRQYRNREETGNGRTYWKPAGWHQINGL
KGSYNHAVDRGHLIGYALVGSLRGFDASTSNPKNIATQAAWANQANSNQSTGQNYYETLVRKALDRHKTVRYRVTLIYDR
DNLLSSGSHIEAKSSDGSLEFNVFIPNVQSGLLFDYATGKVKQTK

Nucleotide


Download         Length: 858 bp        

>NTDB_id=154601 AMM49_RS04690 WP_000163017.1 894776..895633(+) (endA) [Streptococcus agalactiae strain NGBS128]
ATGACAAAAAAACAAAAACAAATAACAGCTTCGATTGTAACTTTGCTTTTTTCATTACTGGCAATAGGGTTAGGTGAAAG
TAAATCTTTGCCTAATGATCACATTTTAAAACAGGTGACAGATTTAATTATTAGTAATGAATCTGGCAAAAATACTTCCC
TTAAAAATATATCAGGAACCCCTAGTAGAGAGTTATCTGAATCTGTTTTGACTAGCAATGTTAAAAAACAATTGGGAACA
AATATAGCTTGGAACCAGTCAGGTGCTTTTATCATTAATCAAAATAAAACAGATTTGAATGCTAAAGTGTCAAGTGCACC
ATATGCTATTAATGAAATAAAGAAGGTTAATAACCAAATTGTTCCAACTAAAGCAAATGCCTTATTAACAAAAGCAACTC
GTCAATATCGAAATCGAGAAGAAACAGGGAATGGTAGAACTTATTGGAAACCAGCTGGATGGCATCAGATAAATGGATTA
AAAGGGAGCTATAACCACGCTGTGGACAGAGGCCATTTAATTGGTTATGCTTTAGTAGGGAGTTTAAGAGGATTTGATGC
CTCCACAAGTAATCCTAAAAATATTGCCACACAAGCAGCTTGGGCAAACCAAGCTAATAGCAACCAATCAACAGGGCAAA
ATTATTATGAAACTTTAGTTCGTAAAGCATTGGATCGTCATAAAACTGTTAGGTATCGTGTGACTTTAATTTATGACAGA
GATAATCTTTTATCTTCGGGATCACATATTGAGGCTAAATCTTCAGATGGAAGTTTAGAATTTAATGTTTTTATTCCTAA
TGTACAATCGGGATTATTATTTGATTATGCAACAGGAAAAGTGAAGCAGACAAAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(87-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

66.379

81.404

0.54
  endA Streptococcus pneumoniae D39

66.379

81.404

0.54
  endA Streptococcus pneumoniae R6

66.379

81.404

0.54
  endA Streptococcus pneumoniae TIGR4

66.379

81.404

0.54

Multiple sequence alignment