Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   AC241_RS18880 Genome accession   NZ_CP012099
Coordinates   3697144..3697923 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus thuringiensis strain HS18-1     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3671845..3733742 3697144..3697923 within 0


Gene organization within MGE regions


Location: 3671845..3733742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AC241_RS18770 (AC241_18785) - 3672416..3673315 (-) 900 WP_016080541.1 polysaccharide deacetylase family protein -
  AC241_RS18775 (AC241_18790) pnp 3673468..3675606 (-) 2139 WP_000076745.1 polyribonucleotide nucleotidyltransferase -
  AC241_RS18780 (AC241_18795) rpsO 3675767..3676036 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  AC241_RS18785 (AC241_18800) ribF 3676137..3677108 (-) 972 WP_016080539.1 bifunctional riboflavin kinase/FAD synthetase -
  AC241_RS18790 (AC241_18805) truB 3677152..3678075 (-) 924 WP_048564393.1 tRNA pseudouridine(55) synthase TruB -
  AC241_RS18795 (AC241_18810) rbfA 3678162..3678518 (-) 357 WP_000776437.1 30S ribosome-binding factor RbfA -
  AC241_RS18800 (AC241_18815) - 3678534..3678815 (-) 282 WP_000634349.1 DUF503 domain-containing protein -
  AC241_RS18805 (AC241_18820) infB 3678812..3680878 (-) 2067 WP_016080536.1 translation initiation factor IF-2 -
  AC241_RS18810 (AC241_18825) - 3680883..3681194 (-) 312 WP_001286522.1 YlxQ family RNA-binding protein -
  AC241_RS18815 (AC241_18830) rnpM 3681195..3681467 (-) 273 WP_000071125.1 RNase P modulator RnpM -
  AC241_RS18820 (AC241_18835) nusA 3681479..3682585 (-) 1107 WP_000102598.1 transcription termination factor NusA -
  AC241_RS18825 (AC241_18840) rimP 3682603..3683073 (-) 471 WP_000359095.1 ribosome maturation factor RimP -
  AC241_RS18830 (AC241_18845) - 3683406..3687707 (-) 4302 WP_050844448.1 PolC-type DNA polymerase III -
  AC241_RS18835 (AC241_18850) - 3687832..3689532 (-) 1701 WP_050844449.1 proline--tRNA ligase -
  AC241_RS18840 (AC241_18855) rseP 3689642..3690898 (-) 1257 WP_050844450.1 RIP metalloprotease RseP -
  AC241_RS18845 (AC241_18860) dxr 3690916..3692058 (-) 1143 WP_000790358.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  AC241_RS18850 (AC241_18865) cdsA 3692082..3692873 (-) 792 WP_000813592.1 phosphatidate cytidylyltransferase -
  AC241_RS18855 (AC241_18870) uppS 3692891..3693667 (-) 777 WP_000971296.1 isoprenyl transferase -
  AC241_RS18860 (AC241_18875) frr 3693753..3694310 (-) 558 WP_000531505.1 ribosome recycling factor -
  AC241_RS18865 (AC241_18880) pyrH 3694313..3695035 (-) 723 WP_000042669.1 UMP kinase -
  AC241_RS18870 (AC241_18885) tsf 3695102..3695989 (-) 888 WP_016080531.1 translation elongation factor Ts -
  AC241_RS18875 (AC241_18890) rpsB 3696093..3696794 (-) 702 WP_000111485.1 30S ribosomal protein S2 -
  AC241_RS18880 (AC241_18895) codY 3697144..3697923 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  AC241_RS18885 (AC241_18900) hslU 3698001..3699392 (-) 1392 WP_000550084.1 ATP-dependent protease ATPase subunit HslU -
  AC241_RS18890 (AC241_18905) hslV 3699415..3699957 (-) 543 WP_000526274.1 ATP-dependent protease proteolytic subunit HslV -
  AC241_RS18895 (AC241_18910) xerC 3700000..3700899 (-) 900 WP_016080529.1 tyrosine recombinase XerC -
  AC241_RS18900 (AC241_18915) trmFO 3700965..3702269 (-) 1305 WP_016080528.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  AC241_RS18905 (AC241_18920) topA 3702318..3704396 (-) 2079 WP_016080527.1 type I DNA topoisomerase -
  AC241_RS18910 (AC241_18925) dprA 3704541..3705410 (-) 870 WP_050844451.1 DNA-processing protein DprA -
  AC241_RS18915 (AC241_18930) sucD 3705498..3706400 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  AC241_RS18920 (AC241_18935) sucC 3706420..3707580 (-) 1161 WP_001020790.1 ADP-forming succinate--CoA ligase subunit beta -
  AC241_RS18925 (AC241_18940) - 3707774..3708547 (-) 774 WP_029443116.1 ribonuclease HII -
  AC241_RS18930 (AC241_18945) ylqF 3708604..3709494 (-) 891 WP_000236702.1 ribosome biogenesis GTPase YlqF -
  AC241_RS18935 (AC241_18950) lepB 3709515..3710066 (-) 552 WP_000711853.1 signal peptidase I -
  AC241_RS18940 (AC241_18955) rplS 3710168..3710512 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  AC241_RS18945 (AC241_18960) trmD 3710659..3711393 (-) 735 WP_016080524.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  AC241_RS18950 (AC241_18965) rimM 3711393..3711908 (-) 516 WP_000170272.1 ribosome maturation factor RimM -
  AC241_RS18955 (AC241_18970) - 3712029..3712256 (-) 228 WP_000737399.1 KH domain-containing protein -
  AC241_RS18960 (AC241_18975) rpsP 3712271..3712543 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  AC241_RS18965 (AC241_18980) ffh 3712644..3713993 (-) 1350 WP_002173106.1 signal recognition particle protein -
  AC241_RS18970 (AC241_18985) - 3714006..3714338 (-) 333 WP_000891061.1 putative DNA-binding protein -
  AC241_RS18975 (AC241_18990) ftsY 3714471..3715460 (-) 990 WP_000007655.1 signal recognition particle-docking protein FtsY -
  AC241_RS18980 (AC241_18995) smc 3715476..3719045 (-) 3570 WP_050844452.1 chromosome segregation protein SMC -
  AC241_RS18985 (AC241_19000) rncS 3719192..3719929 (-) 738 WP_016080522.1 ribonuclease III -
  AC241_RS18990 (AC241_19005) acpP 3719988..3720221 (-) 234 WP_000786062.1 acyl carrier protein -
  AC241_RS18995 (AC241_19010) fabG 3720291..3721031 (-) 741 WP_016080521.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  AC241_RS19000 (AC241_19015) fabD 3721031..3721975 (-) 945 WP_043937877.1 ACP S-malonyltransferase -
  AC241_RS19005 (AC241_19020) plsX 3721990..3722982 (-) 993 WP_016080519.1 phosphate acyltransferase PlsX -
  AC241_RS19010 (AC241_19025) fapR 3722979..3723572 (-) 594 WP_000747349.1 transcription factor FapR -
  AC241_RS19015 (AC241_19030) recG 3723661..3725709 (-) 2049 WP_050844453.1 ATP-dependent DNA helicase RecG -
  AC241_RS19020 (AC241_19035) - 3726000..3727676 (-) 1677 WP_050844454.1 DAK2 domain-containing protein -
  AC241_RS19025 (AC241_19040) - 3727699..3728061 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  AC241_RS19030 (AC241_19045) rpmB 3728438..3728626 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  AC241_RS19035 (AC241_19050) spoVM 3728700..3728780 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  AC241_RS19040 (AC241_19055) - 3728847..3729527 (-) 681 WP_016080517.1 thiamine diphosphokinase -
  AC241_RS19045 (AC241_19060) rpe 3729734..3730378 (-) 645 WP_050844455.1 ribulose-phosphate 3-epimerase -
  AC241_RS19050 (AC241_19065) rsgA 3730381..3731262 (-) 882 WP_001113932.1 ribosome small subunit-dependent GTPase A -
  AC241_RS19055 (AC241_19070) pknB 3731509..3733482 (-) 1974 WP_029443121.1 Stk1 family PASTA domain-containing Ser/Thr kinase -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=151394 AC241_RS18880 WP_000421290.1 3697144..3697923(-) (codY) [Bacillus thuringiensis strain HS18-1]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=151394 AC241_RS18880 WP_000421290.1 3697144..3697923(-) (codY) [Bacillus thuringiensis strain HS18-1]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCTGCAGGGAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATTGAAGCAAACGTGTTCGTTGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAAAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAGTTCCCGGAAGAATATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAATTTAGATGTGAACAGTGCTTATACAGCATTCCCGGTAGAAAACAGAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
TGAGCACATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATCGCTGATCGTGTAGGAATTACTC
GTTCTGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGTTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment