Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   lpt_RS07295 Genome accession   NZ_CP012019
Coordinates   1640309..1641529 (+) Length   406 a.a.
NCBI ID   WP_027226540.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Toronto-20052     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1635309..1646529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  lpt_RS07275 (lpt_07265) - 1636456..1637025 (-) 570 WP_011213801.1 hypoxanthine-guanine phosphoribosyltransferase -
  lpt_RS07280 (lpt_07270) - 1637068..1637394 (-) 327 WP_011213802.1 DUF1820 family protein -
  lpt_RS07285 (lpt_07275) - 1637577..1638320 (-) 744 WP_011213803.1 methyltransferase domain-containing protein -
  lpt_RS07290 (lpt_07280) pilB 1638579..1640303 (+) 1725 WP_011946523.1 type IV-A pilus assembly ATPase PilB Machinery gene
  lpt_RS07295 (lpt_07285) pilC 1640309..1641529 (+) 1221 WP_027226540.1 type II secretion system F family protein Machinery gene
  lpt_RS07300 (lpt_07290) pilD 1641575..1642438 (+) 864 WP_011946525.1 A24 family peptidase Machinery gene
  lpt_RS07305 (lpt_07295) - 1642452..1643657 (-) 1206 WP_013101470.1 cyclic nucleotide-binding domain-containing protein -
  lpt_RS07310 (lpt_07300) - 1643765..1644358 (-) 594 WP_011213808.1 hypothetical protein -
  lpt_RS07315 (lpt_07305) - 1644374..1644829 (-) 456 WP_042233877.1 hypothetical protein -
  lpt_RS07320 (lpt_07310) - 1644963..1645778 (+) 816 WP_011215545.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44705.89 Da        Isoelectric Point: 9.6052

>NTDB_id=150387 lpt_RS07295 WP_027226540.1 1640309..1641529(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Toronto-20052]
MDKNSPPLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVVKKRKPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGALGGVVYSF
FYAKNHSLEFAQTIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFIAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=150387 lpt_RS07295 WP_027226540.1 1640309..1641529(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Toronto-20052]
ATGGATAAAAATAGCCCACCCCTATTAACCTTTCATTATCAAGGCATTAATAAAGCCGGTCAAAAAATGGAGGGTGATAT
TCAAGCCAGAAGCTTGGCAATAGCTAAAGCTGATTTGCGTAAGCAGGGGATTGTTACCAATAAAGTAGTAAAAAAAAGAA
AACCTTTGTTTGATAGAAAAAATAAAAAAATCACACAAGCAGATATTACAGTGTTTAGCCGTCAATTAGCGACGATGATC
GAGTCAGGAATACCATTAGTGCAAGCGTTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATTGAAACGGGGCTAACGCTAGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCAGGCGAAAAATCAGGCTCATTAGATATCATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAAAAAGCTCTCACTTACCCAATTGCTGTTATGGTTGTCGCACTTTTGGTTACTGC
AGGATTATTAATCTATGTAGTTCCTCAATTTGAATCGTTGTTTAAAGGATTTGGAGCTGATTTGCCAGCGATGACTAGAG
CTGTGATCACTATGTCTGAATTTATGCAGGCTTATTGGTATATTATTTTTGGAGCTTTGGGTGGGGTTGTCTATAGCTTT
TTTTATGCTAAAAATCATTCTTTGGAGTTTGCGCAAACCATTGACAGAGTGATGCTAAAATTCCCTGTAATTGGCCCTAT
TTTAGAGAAAGCAGCAATTGCTCGATTCGCGAGGACATTATCCATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCAT
TGAAATCTGTAGCTGGAGCGACTGGGAATATTATTTATGCCAAGGCGACTGATAAAATCAGAGAAGAAGTTGCAACAGGA
CAGCAAATGTTTATTGCTATGGAAAACACTCATTTATTTCCGAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAAAAAATGTTAAGCAAAGTAGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCCCTAAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTGGGTATACTGGTTGGGGGATTGGTAGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

99.754

100

0.998
  pilC Pseudomonas stutzeri DSM 10701

54.208

99.507

0.539
  pilC Acinetobacter baumannii D1279779

53.58

99.754

0.534
  pilC Acinetobacter baylyi ADP1

52.84

99.754

0.527
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

42.25

98.522

0.416
  pilC Vibrio campbellii strain DS40M4

39.163

100

0.392

Multiple sequence alignment