Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   lsr_RS08125 Genome accession   NZ_CP011403
Coordinates   1640383..1641213 (-) Length   276 a.a.
NCBI ID   WP_047036000.1    Uniprot ID   A0A0F7PVU3
Organism   Ligilactobacillus salivarius str. Ren     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1635383..1646213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  lsr_RS08105 (LsR_01563) dhaQ 1636408..1637364 (+) 957 WP_047035998.1 DhaKLM operon coactivator DhaQ -
  lsr_RS08110 (LsR_01564) dhaS 1637365..1637889 (-) 525 WP_003704309.1 dihydroxyacetone kinase transcriptional activator DhaS -
  lsr_RS08115 (LsR_01565) brnQ 1638035..1639417 (-) 1383 WP_047035999.1 branched-chain amino acid transport system II carrier protein -
  lsr_RS08120 - 1639957..1640223 (+) 267 WP_003701014.1 hypothetical protein -
  lsr_RS08125 (LsR_01566) endA 1640383..1641213 (-) 831 WP_047036000.1 DNA/RNA non-specific endonuclease Machinery gene
  lsr_RS08130 (LsR_01567) - 1641582..1642184 (+) 603 WP_003701011.1 nitroreductase family protein -
  lsr_RS08135 (LsR_01568) - 1642239..1644170 (-) 1932 WP_047036001.1 heavy metal translocating P-type ATPase -
  lsr_RS08140 (LsR_01569) - 1644320..1644634 (+) 315 WP_003704272.1 ArsR/SmtB family transcription factor -

Sequence

Protein


Download         Length: 276 a.a.        Molecular weight: 30426.77 Da        Isoelectric Point: 10.4970

>NTDB_id=145621 lsr_RS08125 WP_047036000.1 1640383..1641213(-) (endA) [Ligilactobacillus salivarius str. Ren]
MARKKKNKSNKFMRWLATVAVGVALAAVGVNTNHISTLFNNEVASSSTYNKKDYTPTEEQASVVLTDNVRQQLGGNLSFN
GAGAFIVNNNKTNLNTKVSSAPYAVNEVDSLNRPTVANAWLNRTSRQYKNRQATGNGRTSWKPQGFRQVQNLPGRFKHAY
DRGHLLAYALVGNVRGFDASESNEKNIATQTAWANESASKDSTGQNYYEGLVRKALDRNKQVRYRVTDVYDGNNLVPAGA
HLEAKSSDGSLEFNVFVPNVQTNININYATGQATRK

Nucleotide


Download         Length: 831 bp        

>NTDB_id=145621 lsr_RS08125 WP_047036000.1 1640383..1641213(-) (endA) [Ligilactobacillus salivarius str. Ren]
ATGGCAAGAAAAAAGAAAAATAAATCAAATAAATTTATGAGATGGTTAGCTACCGTTGCTGTAGGGGTTGCTTTAGCAGC
AGTAGGGGTTAATACAAATCATATTAGTACACTATTTAATAATGAGGTTGCAAGTAGTAGTACATATAACAAAAAGGATT
ACACTCCTACTGAGGAACAAGCAAGTGTAGTATTAACAGATAATGTACGCCAACAATTAGGTGGTAATTTAAGCTTTAAT
GGGGCAGGAGCTTTCATTGTAAATAATAATAAGACTAACTTAAATACAAAAGTTTCTAGTGCACCATATGCTGTTAATGA
GGTTGATTCATTGAATCGACCAACTGTTGCGAATGCTTGGCTAAATAGAACTAGTCGTCAATATAAAAATCGCCAAGCTA
CAGGAAATGGACGTACAAGTTGGAAGCCACAAGGATTTAGGCAGGTACAAAATTTGCCTGGTAGATTCAAGCATGCTTAT
GATAGAGGACATTTATTAGCATATGCTCTTGTGGGAAATGTTAGAGGATTTGATGCTTCTGAGTCTAATGAAAAGAATAT
AGCTACTCAAACTGCATGGGCTAATGAATCGGCTTCTAAGGATTCTACCGGACAAAATTACTACGAAGGATTGGTAAGAA
AAGCTTTAGATAGAAACAAGCAGGTTCGTTATCGTGTGACAGATGTCTATGATGGTAATAATCTAGTGCCAGCAGGAGCA
CATTTGGAAGCTAAATCATCAGATGGTTCGCTAGAATTTAATGTATTTGTGCCTAATGTACAAACTAACATAAATATTAA
TTATGCTACAGGACAAGCTACTAGAAAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(83-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7PVU3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

60.538

80.797

0.489
  endA Streptococcus pneumoniae D39

60.538

80.797

0.489
  endA Streptococcus pneumoniae R6

60.538

80.797

0.489
  endA Streptococcus pneumoniae TIGR4

60.538

80.797

0.489

Multiple sequence alignment