Detailed information NTG0143390

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ASL16_RS06640
• Genome accession: NZ_CP013953
• Coordinates: 1333309..1334082 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain NCCP14558 isolate sequencing
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1328309..1339082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASL16_RS06620 (ASL16_06625)	trmFO	1328652..1329959 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ASL16_RS06625 (ASL16_06630)	xerC	1330377..1331273 (+)	897	WP_001015601.1	tyrosine recombinase XerC	-
ASL16_RS06630 (ASL16_06635)	hslV	1331270..1331815 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ASL16_RS06635 (ASL16_06640)	hslU	1331881..1333284 (+)	1404	WP_000379044.1	ATP-dependent protease ATPase subunit HslU	-
ASL16_RS06640 (ASL16_06645)	codY	1333309..1334082 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ASL16_RS06645 (ASL16_06650)	-	1334156..1334230 (+)	75	WP_031761472.1	hypothetical protein	-
ASL16_RS06650 (ASL16_06655)	rpsB	1334429..1335196 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ASL16_RS06655 (ASL16_06660)	-	1335230..1335343 (+)	114	WP_001789890.1	hypothetical protein	-
ASL16_RS06660 (ASL16_06665)	tsf	1335378..1336259 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ASL16_RS06665 (ASL16_06670)	pyrH	1336396..1337118 (+)	723	WP_000057330.1	UMP kinase	-
ASL16_RS06670 (ASL16_06675)	frr	1337137..1337691 (+)	555	WP_001280006.1	ribosome recycling factor	-
ASL16_RS06675 (ASL16_06680)	-	1338064..1338834 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=143390 ASL16_RS06640 WP_000055337.1 1333309..1334082(+) (codY) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=143390 ASL16_RS06640 WP_000055337.1 1333309..1334082(+) (codY) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428