Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   MGAS23530_RS06495 Genome accession   NZ_CP013839
Coordinates   1333487..1334269 (-) Length   260 a.a.
NCBI ID   WP_002992569.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS23530     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1328487..1339269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS23530_RS06470 (MGAS23530_1330) gatB 1328585..1330024 (-) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  MGAS23530_RS06475 (MGAS23530_1331) gatA 1330024..1331490 (-) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  MGAS23530_RS06480 (MGAS23530_1332) gatC 1331490..1331792 (-) 303 WP_031488460.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  MGAS23530_RS06485 (MGAS23530_1333) - 1332024..1332248 (-) 225 WP_014635660.1 putative PEP-binding protein -
  MGAS23530_RS06490 (MGAS23530_1335) - 1332786..1333340 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  MGAS23530_RS06495 (MGAS23530_1336) codY 1333487..1334269 (-) 783 WP_002992569.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  MGAS23530_RS06500 (MGAS23530_1337) - 1334486..1335700 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  MGAS23530_RS06505 (MGAS23530_1338) - 1335931..1336383 (+) 453 WP_002992571.1 universal stress protein -
  MGAS23530_RS06510 (MGAS23530_1339) - 1336506..1337894 (-) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  MGAS23530_RS06515 (MGAS23530_1340) - 1337966..1338931 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28634.75 Da        Isoelectric Point: 4.5065

>NTDB_id=142883 MGAS23530_RS06495 WP_002992569.1 1333487..1334269(-) (codY) [Streptococcus pyogenes strain MGAS23530]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDDEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=142883 MGAS23530_RS06495 WP_002992569.1 1333487..1334269(-) (codY) [Streptococcus pyogenes strain MGAS23530]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACGATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(202-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.765

98.077

0.508