Detailed information NTG0142797

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: MGAS11027_RS07210
• Genome accession: NZ_CP013838
• Coordinates: 1463346..1465685 (-)
• Length: 779 a.a.
• NCBI ID: WP_031488700.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS11027
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1458346..1470685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS11027_RS07170 (MGAS11027_1466)	rpsR	1458636..1458875 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
MGAS11027_RS07175 (MGAS11027_1467)	ssb	1459040..1459531 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
MGAS11027_RS07180 (MGAS11027_1468)	rpsF	1459553..1459843 (-)	291	WP_031488703.1	30S ribosomal protein S6	-
MGAS11027_RS07185 (MGAS11027_1469)	-	1460016..1460309 (-)	294	WP_002983113.1	hypothetical protein	-
MGAS11027_RS07190 (MGAS11027_1470)	mutY	1460477..1461631 (+)	1155	WP_162489831.1	A/G-specific adenine glycosylase	-
MGAS11027_RS07195 (MGAS11027_1471)	-	1461808..1462395 (+)	588	WP_063510276.1	helix-turn-helix domain-containing protein	-
MGAS11027_RS07200 (MGAS11027_1472)	trxA	1462447..1462779 (-)	333	WP_256363924.1	thioredoxin	-
MGAS11027_RS07205 (MGAS11027_1473)	-	1462842..1463342 (-)	501	WP_063510296.1	phosphatase PAP2 family protein	-
MGAS11027_RS07210 (MGAS11027_1474)	mutS/mutS2	1463346..1465685 (-)	2340	WP_031488700.1	endonuclease MutS2	Machinery gene
MGAS11027_RS07215 (MGAS11027_1475)	-	1465834..1466379 (-)	546	WP_002983087.1	CvpA family protein	-
MGAS11027_RS07220 (MGAS11027_1476)	-	1466382..1466690 (-)	309	WP_002993251.1	hypothetical protein	-
MGAS11027_RS07225 (MGAS11027_1477)	rnhC	1466847..1467749 (+)	903	WP_020905449.1	ribonuclease HIII	-
MGAS11027_RS07230 (MGAS11027_1478)	lepB	1467760..1468353 (+)	594	WP_002983074.1	signal peptidase I	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87856.03 Da
• Isoelectric Point: 6.5168

>NTDB_id=142797 MGAS11027_RS07210 WP_031488700.1 1463346..1465685(-) (mutS/mutS2) [Streptococcus pyogenes strain MGAS11027]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELSELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNISFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPILADKGSKIAVFNNIFADIGDEQSIEQNLSTFSSHMTHIVSILNEAD
HNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=142797 MGAS11027_RS07210 WP_031488700.1 1463346..1465685(-) (mutS/mutS2) [Streptococcus pyogenes strain MGAS11027]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
CCAAGAAGAATTATCAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATATTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAGTTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAAAATCTAATCGCTAG
TCGAAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAATATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAATCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CACAATAGTTTAGTTCTCTTTGATGAACTGGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAAACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCTACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGATTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGTCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCGCCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCTCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTTCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAACGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• Smr domain (Smr) (704-778)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-669)

• MutS domain V (MutS_V) (324-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.38	100	0.41