Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   AUQ45_RS07560 Genome accession   NZ_CP013672
Coordinates   1476909..1477691 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain AP53     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1471909..1482691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AUQ45_RS07530 (AUQ45_1500) gatA 1472121..1473587 (-) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  AUQ45_RS07535 (AUQ45_1501) gatC 1473587..1473889 (-) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  AUQ45_RS07545 (AUQ45_1502) - 1474135..1475268 (-) 1134 WP_000564846.1 ISAs1-like element IS1548 family transposase -
  AUQ45_RS07550 (AUQ45_1503) - 1475446..1475670 (-) 225 WP_014635660.1 putative PEP-binding protein -
  AUQ45_RS07555 (AUQ45_1504) - 1476208..1476762 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  AUQ45_RS07560 (AUQ45_1505) codY 1476909..1477691 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  AUQ45_RS07565 (AUQ45_1506) - 1477909..1479123 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  AUQ45_RS07570 (AUQ45_1507) - 1479354..1479806 (+) 453 WP_002992571.1 universal stress protein -
  AUQ45_RS07575 (AUQ45_1508) - 1479929..1481317 (-) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  AUQ45_RS07580 (AUQ45_1509) - 1481389..1482354 (+) 966 WP_002992573.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=141876 AUQ45_RS07560 WP_002983278.1 1476909..1477691(-) (codY) [Streptococcus pyogenes strain AP53]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=141876 AUQ45_RS07560 WP_002983278.1 1476909..1477691(-) (codY) [Streptococcus pyogenes strain AP53]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment