Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | RDF_RS01120 | Genome accession | NZ_CP010867 |
| Coordinates | 190850..191824 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008574.1 | Uniprot ID | A0AAV3JGK6 |
| Organism | Streptococcus agalactiae strain SS1 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 191065..241623 | 190850..191824 | flank | -759 |
Gene organization within MGE regions
Location: 190850..241623
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RDF_RS01120 (RDF_0172) | comYH | 190850..191824 (+) | 975 | WP_001008574.1 | class I SAM-dependent methyltransferase | Machinery gene |
| RDF_RS01125 (RDF_0173) | - | 191856..193049 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| RDF_RS01130 (RDF_0174) | - | 193201..193407 (+) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| RDF_RS11260 (RDF_0175) | - | 193466..193603 (+) | 138 | WP_001865900.1 | hypothetical protein | - |
| RDF_RS01135 (RDF_0176) | - | 193644..194099 (+) | 456 | WP_000905673.1 | hypothetical protein | - |
| RDF_RS01140 (RDF_0177) | - | 194168..194833 (+) | 666 | WP_000008113.1 | CPBP family intramembrane glutamic endopeptidase | - |
| RDF_RS01145 (RDF_0178) | proC | 194854..195624 (-) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| RDF_RS01150 (RDF_0179) | pepA | 195694..196761 (-) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| RDF_RS01155 (RDF_0180) | - | 196946..197185 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| RDF_RS01160 (RDF_0181) | - | 197346..197630 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| RDF_RS01165 (RDF_0182) | - | 197627..197950 (+) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| RDF_RS01170 (RDF_0183) | ytpR | 197983..198609 (+) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| RDF_RS01175 (RDF_0184) | - | 198663..199379 (-) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| RDF_RS01180 (RDF_0185) | ssbA | 199460..199855 (+) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| RDF_RS01185 (RDF_0186) | - | 199979..200623 (+) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| RDF_RS01190 (RDF_0187) | - | 200650..202395 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| RDF_RS01195 (RDF_0188) | - | 202376..203116 (+) | 741 | WP_000697630.1 | LytR/AlgR family response regulator transcription factor | - |
| RDF_RS01200 (RDF_0189) | - | 203286..203741 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| RDF_RS01205 (RDF_0190) | lrgB | 203743..204471 (+) | 729 | WP_000421726.1 | antiholin-like protein LrgB | - |
| RDF_RS01210 (RDF_0191) | - | 204714..206342 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| RDF_RS01215 (RDF_0192) | - | 206455..207432 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| RDF_RS01220 (RDF_0193) | - | 207429..208250 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| RDF_RS01225 (RDF_0194) | - | 208262..209065 (+) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| RDF_RS01230 (RDF_0195) | - | 209049..209675 (+) | 627 | WP_000171311.1 | ABC transporter ATP-binding protein | - |
| RDF_RS01235 (RDF_0196) | treP | 209958..211988 (+) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| RDF_RS01240 (RDF_0197) | treC | 212210..213835 (+) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| RDF_RS01245 (RDF_0198) | - | 214051..216087 (+) | 2037 | WP_000228180.1 | BglG family transcription antiterminator | - |
| RDF_RS01250 (RDF_0199) | - | 216090..216374 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| RDF_RS01255 (RDF_0200) | - | 216387..217742 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| RDF_RS01260 (RDF_0201) | - | 217745..218602 (+) | 858 | WP_000203489.1 | transketolase | - |
| RDF_RS01265 (RDF_0202) | - | 218599..219528 (+) | 930 | WP_001203821.1 | transketolase family protein | - |
| RDF_RS01270 (RDF_0203) | - | 219637..220896 (+) | 1260 | WP_001203071.1 | ferredoxin reductase family protein | - |
| RDF_RS01275 (RDF_0204) | rpsO | 220984..221253 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| RDF_RS01280 (RDF_0205) | pnp | 221634..223763 (+) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| RDF_RS01285 (RDF_0206) | - | 223765..224517 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| RDF_RS01290 (RDF_0207) | cysE | 224526..225110 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| RDF_RS01295 (RDF_0208) | - | 225120..225302 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| RDF_RS01300 (RDF_0209) | cysS | 225299..226642 (+) | 1344 | WP_000591125.1 | cysteine--tRNA ligase | - |
| RDF_RS01305 (RDF_0210) | - | 226635..227021 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| RDF_RS01310 (RDF_0211) | rlmB | 227124..227879 (+) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| RDF_RS01315 (RDF_0212) | - | 227876..228394 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| RDF_RS01320 (RDF_0213) | - | 228487..229347 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| RDF_RS11295 | - | 229884..230003 (+) | 120 | Protein_209 | helix-turn-helix transcriptional regulator | - |
| RDF_RS01325 (RDF_0215) | rplM | 230228..230674 (+) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| RDF_RS01330 (RDF_0216) | rpsI | 230695..231087 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| RDF_RS01335 (RDF_0217) | - | 231215..232369 (-) | 1155 | WP_000022165.1 | tyrosine-type recombinase/integrase | - |
| RDF_RS01340 (RDF_0218) | - | 232433..233023 (-) | 591 | WP_000181098.1 | helix-turn-helix domain-containing protein | - |
| RDF_RS01345 (RDF_0219) | - | 233178..233483 (+) | 306 | WP_000331954.1 | hypothetical protein | - |
| RDF_RS01350 (RDF_0220) | - | 233619..233897 (+) | 279 | WP_000134670.1 | hypothetical protein | - |
| RDF_RS01355 (RDF_0221) | - | 233908..234138 (+) | 231 | WP_000360142.1 | hypothetical protein | - |
| RDF_RS01360 (RDF_0222) | - | 234151..234477 (+) | 327 | WP_000384270.1 | replication initiator protein A | - |
| RDF_RS01365 (RDF_0223) | - | 234481..235110 (+) | 630 | WP_000591148.1 | hypothetical protein | - |
| RDF_RS01370 (RDF_0224) | - | 235423..236298 (+) | 876 | WP_000770113.1 | hypothetical protein | - |
| RDF_RS01375 (RDF_0225) | - | 236334..236768 (+) | 435 | WP_001220479.1 | hypothetical protein | - |
| RDF_RS01380 (RDF_0226) | mobV | 237084..238340 (+) | 1257 | WP_000122832.1 | MobV family relaxase | - |
| RDF_RS01385 (RDF_0227) | - | 238508..238978 (+) | 471 | WP_000130119.1 | hypothetical protein | - |
| RDF_RS01390 (RDF_0228) | - | 239283..239618 (-) | 336 | WP_000384858.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| RDF_RS01395 (RDF_0229) | - | 239608..239895 (-) | 288 | WP_000255538.1 | hypothetical protein | - |
| RDF_RS01400 (RDF_0230) | - | 240298..241518 (-) | 1221 | WP_000156558.1 | tyrosine-type recombinase/integrase | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37046.02 Da Isoelectric Point: 4.5224
>NTDB_id=140378 RDF_RS01120 WP_001008574.1 190850..191824(+) (comYH) [Streptococcus agalactiae strain SS1]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
Nucleotide
Download Length: 975 bp
>NTDB_id=140378 RDF_RS01120 WP_001008574.1 190850..191824(+) (comYH) [Streptococcus agalactiae strain SS1]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
67.302 |
97.222 |
0.654 |
| comYH | Streptococcus mutans UA140 |
67.302 |
97.222 |
0.654 |